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Gene: SHOC2 (SHOC2 leucine rich repeat scaffold protein) Homo sapiens
Symbol: SHOC2
Name: SHOC2 leucine rich repeat scaffold protein
Description: Exhibits protein phosphatase 1 binding activity. Involved in positive regulation of Ras protein signal transduction. Localizes to cytosol; nucleoplasm; and protein phosphatase type 1 complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ60412; KIAA0862; leucine-rich repeat protein SHOC-2; SIAA0862; SOC-2; soc-2 suppressor of clear homolog; SOC2; SUR-8; SUR8
Mus musculus (house mouse) : Shoc2 (Shoc2, leucine rich repeat scaffold protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Shoc2 (SHOC2 leucine-rich repeat scaffold protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Shoc2 (SHOC2 leucine rich repeat scaffold protein)
Pan paniscus (bonobo/pygmy chimpanzee) : SHOC2 (SHOC2 leucine rich repeat scaffold protein)
Canis lupus familiaris (dog) : SHOC2 (SHOC2 leucine rich repeat scaffold protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Shoc2 (SHOC2 leucine rich repeat scaffold protein)
Sus scrofa (pig) : SHOC2 (SHOC2 leucine rich repeat scaffold protein)
Chlorocebus sabaeus (African green monkey) : SHOC2 (SHOC2 leucine rich repeat scaffold protein)
Heterocephalus glaber (naked mole-rat) : Shoc2 (SHOC2 leucine rich repeat scaffold protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl10110,919,547 - 111,013,667 (+)EnsemblGRCh38hg38GRCh38
GRCh38 Ensembl10110,919,593 - 111,013,666 (+)EnsemblGRCh38hg38GRCh38
GRCh3810110,919,370 - 111,013,667 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710112,679,301 - 112,773,425 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610112,713,903 - 112,763,413 (+)NCBINCBI36hg18NCBI36
Build 3410112,713,902 - 112,763,412NCBI
Celera10106,410,898 - 106,505,011 (+)NCBI
Cytogenetic Map10q25.2NCBI
HuRef10106,308,147 - 106,402,174 (+)NCBIHuRef
CHM1_110112,960,945 - 113,055,240 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SHOC2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317750
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.