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Gene: MELTF (melanotransferrin) Homo sapiens
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Symbol: MELTF
Name: melanotransferrin
Description: Exhibits iron ion binding activity. Involved in several processes, including negative regulation of substrate adhesion-dependent cell spreading; positive regulation of extracellular matrix disassembly; and positive regulation of plasminogen activation. Localizes to the anchored component of plasma membrane and cell surface.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5; CD228; FLJ38863; MAP97; melanoma-associated antigen p97, isoform 2; membrane-bound transferrin-like protein; MFI2; MGC4856; MTf; MTF1
Orthologs:
Mus musculus (house mouse) : Meltf (melanotransferrin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Meltf (melanotransferrin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Meltf (melanotransferrin)
Pan paniscus (bonobo/pygmy chimpanzee) : MELTF (melanotransferrin)
Canis lupus familiaris (dog) : MELTF (melanotransferrin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Meltf (melanotransferrin)
Sus scrofa (pig) : MELTF (melanotransferrin)
Chlorocebus sabaeus (African green monkey) : MELTF (melanotransferrin)
Heterocephalus glaber (naked mole-rat) : Meltf (melanotransferrin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl3196,988,621 - 197,029,817 (-)Ensembl
GRCh383197,001,740 - 197,029,817 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373196,728,611 - 196,756,687 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363198,214,553 - 198,241,083 (-)NCBINCBI36hg18NCBI36
Build 343198,234,134 - 198,244,952NCBI
Celera3195,315,485 - 195,343,561 (-)NCBI
Cytogenetic Map3q29NCBI
HuRef3194,028,926 - 194,056,861 (-)NCBIHuRef
CHM1_13196,699,891 - 196,727,973 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MELTF
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317764
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.