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Gene: GUCA1B (guanylate cyclase activator 1B) Homo sapiens
Symbol: GUCA1B
Name: guanylate cyclase activator 1B
Description: Predicted to have guanylate cyclase regulator activity. Predicted to be involved in regulation of guanylate cyclase activity. Localizes to cone photoreceptor outer segment and photoreceptor inner segment. Implicated in retinitis pigmentosa 48.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686E1183; GCAP 2; GCAP2; guanylate cyclase activator 1B (retina); guanylate cyclase-activating protein, photoreceptor 2; guanylyl cyclase-activating protein 2; GUCA2; RP48
Mus musculus (house mouse) : Guca1b (guanylate cyclase activator 1B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Guca1b (guanylate cyclase activator 1B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Guca1b (guanylate cyclase activator 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : GUCA1B (guanylate cyclase activator 1B)
Canis lupus familiaris (dog) : GUCA1B (guanylate cyclase activator 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Guca1b (guanylate cyclase activator 1B)
Sus scrofa (pig) : GUCA1B (guanylate cyclase activator 1B)
Chlorocebus sabaeus (African green monkey) : GUCA1B (guanylate cyclase activator 1B)
Heterocephalus glaber (naked mole-rat) : Guca1b (guanylate cyclase activator 1B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl642,183,284 - 42,194,956 (-)EnsemblGRCh38hg38GRCh38
GRCh38642,183,284 - 42,194,956 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37642,151,022 - 42,162,694 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36642,259,000 - 42,270,672 (-)NCBINCBI36hg18NCBI36
Build 34642,260,530 - 42,270,536NCBI
Celera643,703,483 - 43,715,150 (-)NCBI
Cytogenetic Map6p21.1NCBI
HuRef641,869,069 - 41,880,681 (-)NCBIHuRef
CHM1_1642,153,499 - 42,165,156 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GUCA1B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317826
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.