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Gene: Map4k2 (mitogen-activated protein kinase kinase kinase kinase 2) Mus musculus
Symbol: Map4k2
Name: mitogen-activated protein kinase kinase kinase kinase 2
Description: Predicted to have ATP binding activity; MAP kinase kinase kinase kinase activity; and mitogen-activated protein kinase kinase kinase binding activity. Involved in vesicle targeting. Predicted to localize to the cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI385662; BL44; GCK; germinal center kinase; MAPK/ERK kinase kinase kinase 2; MEK kinase kinase 2; MEKKK 2; MGC143893; MGC143894; mitogen activated protein kinase kinase kinase kinase 2; RAB8 interacting protein; rab8-interacting protein; Rab8ip
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl196,341,135 - 6,355,615 (+)Ensembl
GRCm38196,340,990 - 6,355,619 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37196,341,250 - 6,353,527 (+)NCBIGRCm37mm9NCBIm37
MGSCv36196,341,250 - 6,353,527 (+)NCBImm8
Celera196,214,140 - 6,228,605 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Map4k2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317840
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.