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Gene: Map4k2 (mitogen-activated protein kinase kinase kinase kinase 2) Mus musculus
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Symbol: Map4k2
Name: mitogen-activated protein kinase kinase kinase kinase 2
Description: Predicted to have ATP binding activity; MAP kinase kinase kinase kinase activity; and mitogen-activated protein kinase kinase kinase binding activity. Involved in vesicle targeting. Predicted to localize to the cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI385662; BL44; GCK; germinal center kinase; MAPK/ERK kinase kinase kinase 2; MEK kinase kinase 2; MEKKK 2; MGC143893; MGC143894; mitogen activated protein kinase kinase kinase kinase 2; RAB8 interacting protein; rab8-interacting protein; Rab8ip
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl196,341,135 - 6,355,615 (+)Ensembl
GRCm38196,340,990 - 6,355,619 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37196,341,250 - 6,353,527 (+)NCBIGRCm37mm9NCBIm37
MGSCv36196,341,250 - 6,353,527 (+)NCBImm8
Celera196,214,140 - 6,228,605 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Map4k2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317840
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.