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Gene: Frs2 (fibroblast growth factor receptor substrate 2) Mus musculus
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Symbol: Frs2
Name: fibroblast growth factor receptor substrate 2
Description: Exhibits transmembrane receptor protein tyrosine kinase adaptor activity. Involved in several processes, including animal organ development; organ induction; and regulation of MAPK cascade. Localizes to the cell-cell junction; cytoplasm; and plasma membrane. Is expressed in several structures, including alimentary system; blastocyst; central nervous system; liver; and metanephros. Orthologous to human FRS2 (fibroblast growth factor receptor substrate 2); PARTICIPATES IN brain-derived neurotrophic factor signaling pathway; fibroblast growth factor signaling pathway; neurotrophic factor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; choline.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 4732458E18; C330018A15Rik; FGFR substrate 2; FGFR-signaling adaptor SNT; FRS2-alpha; Frs2alpha; SNT-1; SNT1; suc1-associated neurotrophic factor target 1
Orthologs:
Homo sapiens (human) : FRS2 (fibroblast growth factor receptor substrate 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Frs2 (fibroblast growth factor receptor substrate 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Frs2 (fibroblast growth factor receptor substrate 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FRS2 (fibroblast growth factor receptor substrate 2)
Canis lupus familiaris (dog) : FRS2 (fibroblast growth factor receptor substrate 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Frs2 (fibroblast growth factor receptor substrate 2)
Sus scrofa (pig) : FRS2 (fibroblast growth factor receptor substrate 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3810117,070,127 - 117,148,474 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710116,507,183 - 116,585,530 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610116,474,237 - 116,552,584 (-)NCBImm8
Celera10119,013,278 - 119,091,626 (-)NCBICelera
Cytogenetic Map10 D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Frs2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317843
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.