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Gene: IARS1 (isoleucyl-tRNA synthetase 1) Homo sapiens
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Symbol: IARS1
Name: isoleucyl-tRNA synthetase 1
Description: Exhibits GTPase binding activity and isoleucine-tRNA ligase activity. Involved in isoleucyl-tRNA aminoacylation. Localizes to the aminoacyl-tRNA synthetase multienzyme complex and cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ20736; GRIDHH; IARS; ILERS; ILRS; IRS; isoleucine tRNA ligase 1, cytoplasmic; isoleucine--tRNA ligase; isoleucine--tRNA ligase, cytoplasmic; isoleucine-trna synthetase; isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase, cytoplasmic; PRO0785
Orthologs:
Mus musculus (house mouse) : Iars (isoleucine-tRNA synthetase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Iars1 (isoleucyl-tRNA synthetase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Iars1 (isoleucyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IARS1 (isoleucyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : IARS1 (isoleucyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Iars1 (isoleucyl-tRNA synthetase 1)
Sus scrofa (pig) : IARS1 (isoleucyl-tRNA synthetase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38992,210,207 - 92,293,756 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37994,972,489 - 95,056,038 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36994,012,446 - 94,095,859 (-)NCBINCBI36hg18NCBI36
Build 34992,052,179 - 92,135,522NCBI
Celera965,408,928 - 65,492,347 (-)NCBI
Cytogenetic Map9q22.31NCBI
HuRef964,650,352 - 64,733,811 (-)NCBIHuRef
CHM1_1995,118,853 - 95,202,471 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IARS1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317850
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.