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Gene: Rorc (RAR-related orphan receptor gamma) Mus musculus
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Symbol: Rorc
Name: RAR-related orphan receptor gamma
Description: Exhibits DNA-binding transcription factor activity; sequence-specific DNA binding activity; and transcription coactivator binding activity. Involved in several processes, including hematopoietic or lymphoid organ development; interleukin-17 secretion; and regulation of gene expression. Localizes to external side of plasma membrane and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system; sensory organ; and thyroid gland. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human RORC (RAR related orphan receptor C); INTERACTS WITH (+)-Tetrandrine; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Nr1f3; nuclear receptor ROR-gamma; nuclear receptor RZR-gamma; nuclear receptor subfamily 1 group F member 3; RAR-related orphan receptor C; retinoid-related orphan receptor-gamma; RORgamma; Thor; thymus orphan receptor; TOR
Orthologs:
Homo sapiens (human) : RORC (RAR related orphan receptor C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rorc (RAR-related orphan receptor C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rorc (RAR related orphan receptor C)
Pan paniscus (bonobo/pygmy chimpanzee) : RORC (RAR related orphan receptor C)
Canis lupus familiaris (dog) : RORC (RAR related orphan receptor C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rorc (RAR related orphan receptor C)
Sus scrofa (pig) : RORC (RAR related orphan receptor C)
Chlorocebus sabaeus (African green monkey) : RORC (RAR related orphan receptor C)
Heterocephalus glaber (naked mole-rat) : Rorc (RAR related orphan receptor C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl394,372,794 - 94,398,276 (+)EnsemblGRCm38mm10GRCm38
GRCm38394,372,794 - 94,398,276 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37394,176,748 - 94,202,161 (+)NCBIGRCm37mm9NCBIm37
MGSCv36394,458,190 - 94,483,992 (+)NCBImm8
Celera395,819,177 - 95,843,048 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rorc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317897
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.