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Gene: Wars (tryptophanyl-tRNA synthetase) Mus musculus
Symbol: Wars
Name: tryptophanyl-tRNA synthetase
Description: Exhibits tryptophan-tRNA ligase activity. Involved in tryptophanyl-tRNA aminoacylation. Predicted to localize to the cytosol; nucleus; and protein-containing complex. Human ortholog(s) of this gene implicated in distal hereditary motor neuronopathy type 9. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and skeleton. Orthologous to human WARS1 (tryptophanyl-tRNA synthetase 1); PARTICIPATES IN tryptophan metabolic pathway; INTERACTS WITH 1,4-dichlorobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: TrpRS; tryptophan--tRNA ligase; tryptophan--tRNA ligase, cytoplasmic; tryptophanyl-tRNA synthetase, cytoplasmic; WRS
Homo sapiens (human) : WARS1 (tryptophanyl-tRNA synthetase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Wars1 (tryptophanyl-tRNA synthetase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wars1 (tryptophanyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : WARS1 (tryptophanyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : WARS1 (tryptophanyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wars1 (tryptophanyl-tRNA synthetase 1)
Sus scrofa (pig) : WARS1 (tryptophanyl-tRNA synthetase 1)
Chlorocebus sabaeus (green monkey) : WARS1 (tryptophanyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Wars1 (tryptophanyl-tRNA synthetase 1)
more info ...
Related Pseudogenes: Gm18414  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl12108,860,030 - 108,894,174 (-)Ensembl
GRCm3812108,860,030 - 108,894,175 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712110,098,240 - 110,132,384 (-)NCBIGRCm37mm9NCBIm37
MGSCv3612109,307,841 - 109,341,004 (-)NCBImm8
Celera12110,098,849 - 110,127,409 (-)NCBICelera
Cytogenetic Map12 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Wars
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317962
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.