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Gene: Wars (tryptophanyl-tRNA synthetase) Mus musculus
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Symbol: Wars
Name: tryptophanyl-tRNA synthetase
Description: Exhibits tryptophan-tRNA ligase activity. Involved in tryptophanyl-tRNA aminoacylation. Predicted to localize to the cytosol; nucleus; and protein-containing complex. Human ortholog(s) of this gene implicated in distal hereditary motor neuronopathy type 9. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and skeleton. Orthologous to human WARS1 (tryptophanyl-tRNA synthetase 1); PARTICIPATES IN tryptophan metabolic pathway; INTERACTS WITH 1,4-dichlorobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: TrpRS; tryptophan--tRNA ligase; tryptophan--tRNA ligase, cytoplasmic; tryptophanyl-tRNA synthetase, cytoplasmic; WRS
Orthologs:
Homo sapiens (human) : WARS1 (tryptophanyl-tRNA synthetase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Wars1 (tryptophanyl-tRNA synthetase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wars1 (tryptophanyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : WARS1 (tryptophanyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : WARS1 (tryptophanyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wars1 (tryptophanyl-tRNA synthetase 1)
Sus scrofa (pig) : WARS1 (tryptophanyl-tRNA synthetase 1)
Chlorocebus sabaeus (green monkey) : WARS1 (tryptophanyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Wars1 (tryptophanyl-tRNA synthetase 1)
more info ...
Related Pseudogenes: Gm18414  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl12108,860,030 - 108,894,174 (-)Ensembl
GRCm3812108,860,030 - 108,894,175 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712110,098,240 - 110,132,384 (-)NCBIGRCm37mm9NCBIm37
MGSCv3612109,307,841 - 109,341,004 (-)NCBImm8
Celera12110,098,849 - 110,127,409 (-)NCBICelera
Cytogenetic Map12 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Wars
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317962
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.