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Gene: LCP1 (lymphocyte cytosolic protein 1) Homo sapiens
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Symbol: LCP1
Name: lymphocyte cytosolic protein 1
Description: Exhibits GTPase binding activity; actin filament binding activity; and integrin binding activity. Involved in several processes, including extracellular matrix disassembly; positive regulation of podosome assembly; and protein kinase A signaling. Localizes to several cellular components, including the actin cytoskeleton; focal adhesion; and ruffle. Colocalizes with the perinuclear region of cytoplasm and stress fiber.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)); CP64; DKFZp781A23186; epididymis secretory protein Li 37; FLJ25423; FLJ26114; FLJ39956; HEL-S-37; L-PLASTIN; L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P); LC64P; LCP-1; LPL; lymphocyte cytosolic protein 1 (L-plastin); Lymphocyte cytosolic protein-1 (plasmin); plastin 2; plastin-2; PLS2
Orthologs:
Mus musculus (house mouse) : Lcp1 (lymphocyte cytosolic protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lcp1 (lymphocyte cytosolic protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lcp1 (lymphocyte cytosolic protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LCP1 (lymphocyte cytosolic protein 1)
Canis lupus familiaris (dog) : LCP1 (lymphocyte cytosolic protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lcp1 (lymphocyte cytosolic protein 1)
Sus scrofa (pig) : LCP1 (lymphocyte cytosolic protein 1)
Chlorocebus sabaeus (African green monkey) : LCP1 (lymphocyte cytosolic protein 1)
Heterocephalus glaber (naked mole-rat) : Lcp1 (lymphocyte cytosolic protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1346,125,920 - 46,211,871 (-)Ensembl
GRCh381346,125,923 - 46,182,177 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371346,700,058 - 46,756,459 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361345,598,060 - 45,654,395 (-)NCBINCBI36hg18NCBI36
Build 341345,598,059 - 45,654,395NCBI
Celera1327,755,067 - 27,811,461 (-)NCBI
Cytogenetic Map13q14.13NCBI
HuRef1327,497,877 - 27,554,218 (-)NCBIHuRef
CHM1_11346,669,191 - 46,725,269 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on LCP1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317977
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.