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Gene: Nhlh2 (nescient helix loop helix 2) Mus musculus
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Symbol: Nhlh2
Name: nescient helix loop helix 2
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in mating behavior; ovulation cycle; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; genitourinary system; head mesenchyme derived from neural crest; and sensory organ. Orthologous to human NHLH2 (nescient helix-loop-helix 2); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6230401I09Rik; bHLHa; bHLHa34; helix-loop-helix protein 2; Hen; HEN-2; Hen2; NS; Nsc; Nscl-2; NSCL2
Orthologs:
Homo sapiens (human) : NHLH2 (nescient helix-loop-helix 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nhlh2 (nescient helix loop helix 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nhlh2 (nescient helix-loop-helix 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NHLH2 (nescient helix-loop-helix 2)
Canis lupus familiaris (dog) : NHLH2 (nescient helix-loop-helix 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nhlh2 (nescient helix-loop-helix 2)
Sus scrofa (pig) : NHLH2 (nescient helix-loop-helix 2)
Chlorocebus sabaeus (African green monkey) : NHLH2 (nescient helix-loop-helix 2)
Heterocephalus glaber (naked mole-rat) : Nhlh2 (nescient helix-loop-helix 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl3102,010,076 - 102,015,492 (+)EnsemblGRCm38mm10GRCm38
GRCm383102,010,111 - 102,015,492 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373101,814,068 - 101,819,415 (+)NCBIGRCm37mm9NCBIm37
MGSCv363102,139,216 - 102,143,567 (+)NCBImm8
Celera3104,213,826 - 104,219,176 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nhlh2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317986
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.