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Gene: Inf2 (inverted formin, FH2 and WH2 domain containing) Mus musculus
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Symbol: Inf2
Name: inverted formin, FH2 and WH2 domain containing
Description: Predicted to have Rho GTPase binding activity and actin binding activity. Involved in regulation of cellular component size. Predicted to localize to the perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate E and focal segmental glomerulosclerosis 5. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system; and nervous system. Orthologous to human INF2 (inverted formin, FH2 and WH2 domain containing); INTERACTS WITH 3,3',4,4'-tetrachlorobiphenyl; aflatoxin B1; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610204M08Rik; AA589465; AW125550; EG629699; formin, inverted; inverted formin-2; MGC107363; MGC143801; MGC143802
Orthologs:
Homo sapiens (human) : INF2 (inverted formin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Inf2 (inverted formin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Inf2 (inverted formin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : INF2 (inverted formin 2)
Canis lupus familiaris (dog) : LOC490877 (inverted formin, FH2 and WH2 domain containing)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Inf2 (inverted formin 2)
Sus scrofa (pig) : INF2 (inverted formin 2)
Chlorocebus sabaeus (green monkey) : INF2 (inverted formin 2)
Heterocephalus glaber (naked mole-rat) : Inf2 (inverted formin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl12112,588,784 - 112,615,557 (+)Ensembl
GRCm3812112,588,744 - 112,615,557 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712113,826,995 - 113,853,768 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612113,052,465 - 113,063,365 (+)NCBImm8
Celera12113,802,332 - 113,829,237 (+)NCBICelera
Cytogenetic Map12 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Inf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318069
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.