Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TRIO (trio Rho guanine nucleotide exchange factor) Homo sapiens
Analyze
Symbol: TRIO
Name: trio Rho guanine nucleotide exchange factor
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity. Predicted to be involved in negative regulation of fat cell differentiation. Predicted to localize to cytosol. Implicated in autosomal dominant non-syndromic intellectual disability and autosomal dominant non-syndromic intellectual disability 44.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ARHGEF23; FLJ42780; MEBAS; MRD44; MRD63; PTPRF-interacting protein; tgat; triple functional domain (PTPRF interacting); triple functional domain protein
Orthologs:
Mus musculus (house mouse) : Trio (triple functional domain (PTPRF interacting))  MGI  Alliance
Rattus norvegicus (Norway rat) : Trio (trio Rho guanine nucleotide exchange factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trio (trio Rho guanine nucleotide exchange factor)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIO (trio Rho guanine nucleotide exchange factor)
Canis lupus familiaris (dog) : TRIO (trio Rho guanine nucleotide exchange factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trio (trio Rho guanine nucleotide exchange factor)
Sus scrofa (pig) : TRIO (trio Rho guanine nucleotide exchange factor)
Chlorocebus sabaeus (African green monkey) : TRIO (trio Rho guanine nucleotide exchange factor)
Heterocephalus glaber (naked mole-rat) : Trio (trio Rho guanine nucleotide exchange factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl514,143,342 - 14,532,128 (+)EnsemblGRCh38hg38GRCh38
GRCh38514,143,342 - 14,510,204 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37514,143,817 - 14,510,313 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36514,196,829 - 14,562,458 (+)NCBINCBI36hg18NCBI36
Build 34514,196,828 - 14,562,457NCBI
Celera514,168,142 - 14,532,209 (+)NCBI
Cytogenetic Map5p15.2NCBI
HuRef514,242,473 - 14,481,695 (+)NCBIHuRef
CHM1_1514,143,936 - 14,510,180 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TRIO
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318084
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.