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Gene: Hoxd13 (homeobox D13) Mus musculus
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Symbol: Hoxd13
Name: homeobox D13
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including male genitalia development; morphogenesis of an epithelium; and regulation of branching involved in prostate gland morphogenesis. Localizes to the nucleus. Used to study synpolydactyly. Human ortholog(s) of this gene implicated in brachydactyly (multiple); brachydactyly-syndactyly syndrome; clubfoot; and cryptorchidism. Is expressed in several structures, including genitourinary system; hair root sheath matrix; hindgut; limb; and tail. Orthologous to human HOXD13 (homeobox D13); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: homeo box D13; homeobox protein Hox-4.8; homeobox protein Hox-D13; Hox-4.8; spdh
Orthologs:
Homo sapiens (human) : HOXD13 (homeobox D13)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hoxd13 (homeo box D13)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hoxd13 (homeobox D13)
Pan paniscus (bonobo/pygmy chimpanzee) : HOXD13 (homeobox D13)
Canis lupus familiaris (dog) : HOXD13 (homeobox D13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hoxd13 (homeobox D13)
Sus scrofa (pig) : HOXD13 (homeobox D13)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl274,668,310 - 74,671,599 (+)Ensembl
GRCm38274,668,225 - 74,671,603 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37274,506,367 - 74,509,655 (+)NCBIGRCm37mm9NCBIm37
MGSCv36274,469,149 - 74,470,975 (+)NCBImm8
Celera276,338,416 - 76,341,707 (+)NCBICelera
Cytogenetic Map2 C3NCBI
cM Map244.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hoxd13
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318173
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.