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Gene: Hoxd13 (homeobox D13) Mus musculus
Symbol: Hoxd13
Name: homeobox D13
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including male genitalia development; morphogenesis of an epithelium; and regulation of branching involved in prostate gland morphogenesis. Localizes to the nucleus. Used to study synpolydactyly. Human ortholog(s) of this gene implicated in brachydactyly (multiple); brachydactyly-syndactyly syndrome; clubfoot; and cryptorchidism. Is expressed in several structures, including genitourinary system; hair root sheath matrix; hindgut; limb; and tail. Orthologous to human HOXD13 (homeobox D13); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: homeo box D13; homeobox protein Hox-4.8; homeobox protein Hox-D13; Hox-4.8; spdh
Homo sapiens (human) : HOXD13 (homeobox D13)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hoxd13 (homeo box D13)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hoxd13 (homeobox D13)
Pan paniscus (bonobo/pygmy chimpanzee) : HOXD13 (homeobox D13)
Canis lupus familiaris (dog) : HOXD13 (homeobox D13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hoxd13 (homeobox D13)
Sus scrofa (pig) : HOXD13 (homeobox D13)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl274,668,310 - 74,671,599 (+)Ensembl
GRCm38274,668,225 - 74,671,603 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37274,506,367 - 74,509,655 (+)NCBIGRCm37mm9NCBIm37
MGSCv36274,469,149 - 74,470,975 (+)NCBImm8
Celera276,338,416 - 76,341,707 (+)NCBICelera
Cytogenetic Map2 C3NCBI
cM Map244.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hoxd13
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318173
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.