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Gene: TAF8 (TATA-box binding protein associated factor 8) Homo sapiens
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Symbol: TAF8
Name: TATA-box binding protein associated factor 8
Description: This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 43; FLJ32821; hTAFII43; II; protein taube nuss; TAF; TAF(II)43; TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa; TAFII-43; TAFII43; TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa; TATA box binding protein associated factor 8; taube nuss homolog; TBN; TBP-associated factor 43 kDa; TBP-associated factor 8; TBP-associated factor TAFII43; TBP-associated factor, RNA polymerase II, 43 kD; transcription initiation factor TFIID 43 kDa subunit; transcription initiation factor TFIID subunit 8
Orthologs:
Mus musculus (house mouse) : Taf8 (TATA-box binding protein associated factor 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Taf8 (TATA-box binding protein associated factor 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Taf8 (TATA-box binding protein associated factor 8)
Pan paniscus (bonobo/pygmy chimpanzee) : TAF8 (TATA-box binding protein associated factor 8)
Canis lupus familiaris (dog) : TAF8 (TATA-box binding protein associated factor 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Taf8 (TATA-box binding protein associated factor 8)
Sus scrofa (pig) : TAF8 (TATA-box binding protein associated factor 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38642,050,522 - 42,083,278 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37642,018,251 - 42,055,093 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36642,126,229 - 42,156,622 (+)NCBINCBI36hg18NCBI36
Build 34642,126,237 - 42,163,177NCBI
Celera643,570,718 - 43,601,096 (+)NCBI
Cytogenetic Map6p21.1NCBI
HuRef641,736,207 - 41,766,572 (+)NCBIHuRef
CHM1_1642,020,783 - 42,051,144 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TAF8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318181
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.