Gene: TOR1B (torsin family 1 member B) Homo sapiens
Analyze
Symbol:
TOR1B
Name:
torsin family 1 member B
Description:
Exhibits ATPase activity and identical protein binding activity. Involved in endoplasmic reticulum organization. Localizes to the endoplasmic reticulum lumen and nuclear envelope.
Type:
protein-coding
RefSeq Status:
REVIEWED
Also known as:
DQ1; MGC4386; torsin ATPase-1B; torsin B; torsin family 1, member B (torsin B); torsin-1B
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Mus musculus (house mouse):
Tor1b (torsin family 1, member B) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Rattus norvegicus (Norway rat):
Tor1b (torsin family 1, member B) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Chinchilla lanigera (long-tailed chinchilla):
Tor1b (torsin family 1 member B) NCBI
Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):
TOR1B (torsin family 1 member B) NCBI
Ortholog
Canis lupus familiaris (dog):
TOR1B (torsin family 1 member B) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Tor1b (torsin family 1 member B) NCBI
Ortholog
Sus scrofa (pig):
TOR1B (torsin family 1 member B) HGNC
EggNOG, Ensembl, NCBI, OMA, OrthoDB, Panther, Treefam
Other homologs 2
Rattus norvegicus (Norway rat):
Tor1a (torsin family 1, member A) HGNC
OrthoDB
Mus musculus (house mouse):
Tor1a (torsin family 1, member A (torsin A)) HGNC
OrthoDB
Canis lupus familiaris (dog):
TOR1A (torsin family 1 member A) HGNC
OrthoDB
Sus scrofa (pig):
TOR1A (torsin family 1 member A) HGNC
OrthoDB
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Tor1b (torsin family 1, member B)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Mus musculus (house mouse):
Tor1b (torsin family 1, member B)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Danio rerio (zebrafish):
tor1 (torsin family 1)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Caenorhabditis elegans (roundworm):
ooc-5
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Drosophila melanogaster (fruit fly):
Torsin
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Caenorhabditis elegans (roundworm):
tor-1
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Caenorhabditis elegans (roundworm):
tor-2
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Related Pseudogenes:
TOR1BP1
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 9 129,803,143 - 129,811,424 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh37 9 132,565,428 - 132,573,563 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 9 131,605,253 - 131,613,381 (+) NCBI NCBI36 hg18 NCBI36 Build 34 9 129,644,985 - 129,653,114 NCBI Celera 9 103,216,467 - 103,224,595 (+) NCBI Cytogenetic Map 9 q34.11 NCBI HuRef 9 102,164,317 - 102,172,400 (+) NCBI HuRef CHM1_1 9 132,714,556 - 132,722,697 (+) NCBI CHM1_1
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Gene-Chemical Interaction Annotations
17alpha-ethynylestradiol multiple interactions ISO RGD:1318196 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TOR1B mRNA CTD PMID:17942748 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:1308431 6480464 2 more ... CTD PMID:27291303 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1318196 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TOR1B mRNA, [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of TOR1B mRNA CTD PMID:17942748 , PMID:25975270 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1318196 6480464 Tetrachlorodibenzodioxin affects the expression of TOR1B mRNA CTD PMID:21570461 2,4-dinitrotoluene affects expression ISO RGD:1308431 6480464 2, 4-dinitrotoluene affects the expression of TOR1B mRNA CTD PMID:21346803 2-hydroxypropanoic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of TOR1B mRNA CTD PMID:30851411 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO RGD:1318196 6480464 3 more ... CTD PMID:19467301 3,4-methylenedioxymethamphetamine increases expression ISO RGD:1318196 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of TOR1B mRNA CTD PMID:20188158 acrylamide increases expression ISO RGD:1308431 6480464 Acrylamide results in increased expression of TOR1B mRNA CTD PMID:28959563 aflatoxin B1 increases expression ISO RGD:1318196 6480464 Aflatoxin B1 results in increased expression of TOR1B mRNA CTD PMID:19770486 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of TOR1B mRNA CTD PMID:15498508 atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of TOR1B mRNA CTD PMID:22378314 benzene increases expression EXP 6480464 Benzene results in increased expression of TOR1B mRNA CTD PMID:19162166 benzo[a]pyrene multiple interactions ISO RGD:1318196 6480464 [Potassium Dichromate co-treated with potassium chromate(VI)] inhibits the reaction [Benzo(a)pyrene results in increased expression of TOR1B mRNA] CTD PMID:14625279 benzo[a]pyrene increases expression ISO RGD:1318196 6480464 Benzo(a)pyrene results in increased expression of TOR1B mRNA CTD PMID:14625279 more ... bis(2-ethylhexyl) phthalate increases expression ISO RGD:1318196 6480464 Diethylhexyl Phthalate results in increased expression of TOR1B mRNA CTD PMID:21318169 bisphenol A increases expression ISO RGD:1308431 6480464 bisphenol A results in increased expression of TOR1B mRNA CTD PMID:27178563 bisphenol A affects expression ISO RGD:1308431 6480464 bisphenol A affects the expression of TOR1B mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:1308431 6480464 [bisphenol A co-treated with Testosterone] results in increased expression of TOR1B mRNA CTD PMID:26496021 cadmium dichloride decreases expression ISO RGD:1308431 6480464 Cadmium Chloride results in decreased expression of TOR1B mRNA CTD PMID:25993096 carbon nanotube increases expression ISO RGD:1318196 6480464 Nanotubes, Carbon analog results in increased expression of TOR1B mRNA CTD PMID:25620056 cyproconazole increases expression ISO RGD:1318196 6480464 cyproconazole results in increased expression of TOR1B mRNA CTD PMID:22334560 decabromodiphenyl ether increases expression ISO RGD:1308431 6480464 decabromobiphenyl ether results in increased expression of TOR1B mRNA CTD PMID:23640034 epoxiconazole increases expression ISO RGD:1318196 6480464 epoxiconazole results in increased expression of TOR1B mRNA CTD PMID:22334560 fenofibrate increases expression ISO RGD:1318196 6480464 Fenofibrate results in increased expression of TOR1B mRNA CTD PMID:21318169 fenofibrate multiple interactions ISO RGD:1318196 6480464 PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR1B mRNA] CTD PMID:21318169 flutamide increases expression ISO RGD:1308431 6480464 Flutamide results in increased expression of TOR1B mRNA CTD PMID:24136188 N-methyl-N-nitrosourea decreases expression ISO RGD:1318196 6480464 Methylnitrosourea results in decreased expression of TOR1B mRNA CTD PMID:25270620 nickel atom decreases expression EXP 6480464 Nickel results in decreased expression of TOR1B mRNA CTD PMID:23195993 paracetamol affects expression ISO RGD:1318196 6480464 Acetaminophen affects the expression of TOR1B mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of TOR1B mRNA CTD PMID:22230336 pirinixic acid multiple interactions ISO RGD:1318196 6480464 PPARA protein affects the reaction [pirinixic acid results in increased expression of TOR1B mRNA] CTD PMID:21318169 pirinixic acid increases expression ISO RGD:1318196 6480464 pirinixic acid results in increased expression of TOR1B mRNA CTD PMID:18301758 , PMID:21318169 potassium chromate multiple interactions ISO RGD:1318196 6480464 [Potassium Dichromate co-treated with potassium chromate(VI)] inhibits the reaction [Benzo(a)pyrene results in increased expression of TOR1B mRNA] CTD PMID:14625279 potassium dichromate multiple interactions ISO RGD:1318196 6480464 [Potassium Dichromate co-treated with potassium chromate(VI)] inhibits the reaction [Benzo(a)pyrene results in increased expression of TOR1B mRNA] CTD PMID:14625279 propiconazole increases expression ISO RGD:1318196 6480464 propiconazole results in increased expression of TOR1B mRNA CTD PMID:21278054 , PMID:22334560 rac-lactic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of TOR1B mRNA CTD PMID:30851411 resveratrol increases expression ISO RGD:1318196 6480464 resveratrol results in increased expression of TOR1B protein CTD PMID:25505154 sodium arsenate decreases expression ISO RGD:1318196 6480464 sodium arsenate results in decreased expression of TOR1B mRNA CTD PMID:21795629 sodium arsenite increases expression ISO RGD:1318196 6480464 sodium arsenite results in increased expression of TOR1B protein CTD PMID:29044176 sodium fluoride decreases expression ISO RGD:1318196 6480464 Sodium Fluoride results in decreased expression of TOR1B mRNA CTD PMID:27862939 tamibarotene increases expression EXP 6480464 tamibarotene results in increased expression of TOR1B mRNA CTD PMID:15498508 testosterone multiple interactions ISO RGD:1308431 6480464 [bisphenol A co-treated with Testosterone] results in increased expression of TOR1B mRNA CTD PMID:26496021 tetrachloromethane increases expression ISO RGD:1318196 6480464 Carbon Tetrachloride results in increased expression of TOR1B mRNA CTD PMID:27339419 trichloroethene increases methylation ISO RGD:1308431 6480464 Trichloroethylene results in increased methylation of TOR1B gene CTD PMID:27618143 urethane increases expression EXP 6480464 Urethane results in increased expression of TOR1B mRNA CTD PMID:28818685 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of TOR1B mRNA CTD PMID:25979313 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of TOR1B mRNA CTD PMID:28001369 zinc atom multiple interactions EXP 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of TOR1B mRNA CTD PMID:18593933 zinc(0) multiple interactions EXP 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of TOR1B mRNA CTD PMID:18593933 
Gene-Chemical Interaction Annotations
