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Gene: LOXL2 (lysyl oxidase like 2) Homo sapiens
Symbol: LOXL2
Name: lysyl oxidase like 2
Description: Exhibits metal ion binding activity; oligosaccharide binding activity; and protein-lysine 6-oxidase activity. Involved in several processes, including collagen fibril organization; peptidyl-lysine oxidation; and response to copper ion. Localizes to several cellular components, including chromatin; endoplasmic reticulum; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: LOR; LOR2; lysyl oxidase homolog 2; lysyl oxidase related 2; lysyl oxidase-like 2 delta e13; lysyl oxidase-like protein 2; lysyl oxidase-related protein 2; lysyl oxidase-related protein WS9-14; WS9-14
Mus musculus (house mouse) : Loxl2 (lysyl oxidase-like 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Loxl2 (lysyl oxidase-like 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Loxl2 (lysyl oxidase like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LOXL2 (lysyl oxidase like 2)
Canis lupus familiaris (dog) : LOXL2 (lysyl oxidase like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Loxl2 (lysyl oxidase like 2)
Sus scrofa (pig) : LOXL2 (lysyl oxidase like 2)
Chlorocebus sabaeus (African green monkey) : LOXL2 (lysyl oxidase like 2)
Heterocephalus glaber (naked mole-rat) : Loxl2 (lysyl oxidase like 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl823,296,897 - 23,425,328 (-)EnsemblGRCh38hg38GRCh38
GRCh38823,296,897 - 23,404,120 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37823,154,410 - 23,261,722 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36823,210,355 - 23,317,667 (-)NCBINCBI36hg18NCBI36
Build 34823,210,640 - 23,317,575NCBI
Celera822,116,981 - 22,224,289 (-)NCBI
Cytogenetic Map8p21.3NCBI
HuRef821,700,441 - 21,807,111 (-)NCBIHuRef
CHM1_1823,356,541 - 23,463,832 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LOXL2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318201
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.