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Gene: NKD1 (NKD inhibitor of WNT signaling pathway 1) Homo sapiens
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Symbol: NKD1
Name: NKD inhibitor of WNT signaling pathway 1
Description: Predicted to have PDZ domain binding activity and calcium ion binding activity. Involved in negative regulation of canonical Wnt signaling pathway and positive regulation of protein catabolic process. Localizes to protein phosphatase type 2A complex.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Dvl-binding protein; FLJ11639; FLJ13722; FLJ20269; hNkd; hNkd1; naked cuticle homolog 1; naked cuticle homolog 1 (Drosophila); naked cuticle-1; naked-1; Naked1; NKD1, WNT signaling pathway inhibitor; protein naked cuticle homolog 1
Orthologs:
Mus musculus (house mouse) : Nkd1 (naked cuticle 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nkd1 (NKD inhibitor of WNT signaling pathway 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nkd1 (NKD inhibitor of WNT signaling pathway 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NKD1 (NKD inhibitor of WNT signaling pathway 1)
Canis lupus familiaris (dog) : NKD1 (NKD inhibitor of WNT signaling pathway 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nkd1 (NKD inhibitor of WNT signaling pathway 1)
Sus scrofa (pig) : NKD1 (NKD inhibitor of WNT signaling pathway 1)
Chlorocebus sabaeus (African green monkey) : NKD1 (NKD inhibitor of WNT signaling pathway 1)
Heterocephalus glaber (naked mole-rat) : Nkd1 (NKD inhibitor of WNT signaling pathway 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1650,548,396 - 50,649,249 (+)EnsemblGRCh38hg38GRCh38
GRCh381650,548,396 - 50,649,249 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371650,582,241 - 50,674,771 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361649,139,742 - 49,226,142 (+)NCBINCBI36hg18NCBI36
Build 341649,139,741 - 49,226,142NCBI
Celera1635,097,548 - 35,183,963 (+)NCBI
Cytogenetic Map16q12.1NCBI
HuRef1636,470,058 - 36,562,565 (+)NCBIHuRef
CHM1_11651,989,797 - 52,082,309 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NKD1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318289
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.