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Gene: Sp5 (trans-acting transcription factor 5) Mus musculus
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Symbol: Sp5
Name: trans-acting transcription factor 5
CRRD ID: 1318303
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including bone morphogenesis; negative regulation of transcription by RNA polymerase II; and post-anal tail morphogenesis. Predicted to localize to nucleus. Is expressed in several structures, including brain; branchial arch; embryo ectoderm; embryo mesenchyme; and tooth. Orthologous to human SP5 (Sp5 transcription factor); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC144801; MGC144802; transcription factor Sp5
Orthologs:
Homo sapiens (human) : SP5 (Sp5 transcription factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sp5 (Sp5 transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sp5 (Sp5 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SP5 (Sp5 transcription factor)
Canis lupus familiaris (dog) : SP5 (Sp5 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sp5 (Sp5 transcription factor)
Sus scrofa (pig) : SP5 (Sp5 transcription factor)
Chlorocebus sabaeus (African green monkey) : SP5 (Sp5 transcription factor)
Heterocephalus glaber (naked mole-rat) : Sp5 (Sp5 transcription factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl270,474,923 - 70,477,729 (+)EnsemblGRCm38mm10GRCm38
GRCm38270,474,923 - 70,477,726 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37270,312,980 - 70,315,783 (+)NCBIGRCm37mm9NCBIm37
MGSCv36270,275,762 - 70,278,565 (+)NCBImm8
Celera272,140,603 - 72,143,373 (+)NCBICelera
Cytogenetic Map2C2NCBI
cM Map241.49NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sp5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318303
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-08-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.