1,1-dichloroethene increases expression EXP 6480464 vinylidene chloride results in increased expression of POLD4 mRNA CTD PMID:26682919 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of POLD4 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POLD4 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of POLD4 mRNA CTD PMID:17942748 17beta-estradiol decreases expression ISO RGD:1318336 6480464 Estradiol results in decreased expression of POLD4 mRNA CTD PMID:16474171 , PMID:23019147 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POLD4 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of POLD4 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1318336 6480464 Tetrachlorodibenzodioxin results in increased expression of POLD4 mRNA CTD PMID:20106945 , PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1308519 6480464 Tetrachlorodibenzodioxin results in increased expression of POLD4 mRNA CTD PMID:18796159 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of POLD4 mRNA CTD PMID:17942748 2,4-dinitrotoluene affects expression ISO RGD:1308519 6480464 2, 4-dinitrotoluene affects the expression of POLD4 mRNA CTD PMID:21346803 2-butoxyethanol decreases expression EXP 6480464 n-butoxyethanol results in decreased expression of POLD4 mRNA CTD PMID:19812364 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of POLD4 mRNA CTD PMID:20188158 aflatoxin B1 increases expression ISO RGD:1318336 6480464 Aflatoxin B1 results in increased expression of POLD4 mRNA CTD PMID:21641981 , PMID:27153756 all-trans-retinoic acid increases expression ISO RGD:1318336 6480464 Tretinoin results in increased expression of POLD4 mRNA CTD PMID:15498508 , PMID:16054129 antirheumatic drug decreases expression ISO RGD:1318336 6480464 Antirheumatic Agents results in decreased expression of POLD4 mRNA CTD PMID:24449571 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of POLD4 mRNA CTD PMID:23650126 arsane increases methylation ISO RGD:1318336 6480464 Arsenic results in increased methylation of POLD4 promoter CTD PMID:21291286 arsenic atom increases methylation ISO RGD:1318336 6480464 Arsenic results in increased methylation of POLD4 promoter CTD PMID:21291286 arsenous acid increases expression ISO RGD:1318336 6480464 Arsenic Trioxide results in increased expression of POLD4 mRNA CTD PMID:22521957 azathioprine increases expression ISO RGD:1318336 6480464 Azathioprine results in increased expression of POLD4 mRNA CTD PMID:22623647 benzo[a]pyrene affects expression ISO RGD:1318336 6480464 Benzo(a)pyrene affects the expression of POLD4 mRNA CTD PMID:20106945 , PMID:20624995 benzo[a]pyrene increases expression ISO RGD:1318336 6480464 Benzo(a)pyrene results in increased expression of POLD4 mRNA CTD PMID:21632981 , PMID:22316170 bisphenol A decreases expression ISO RGD:1318336 6480464 bisphenol A results in decreased expression of POLD4 mRNA CTD PMID:16474171 bisphenol A increases expression ISO RGD:1308519 6480464 bisphenol A results in increased expression of POLD4 mRNA CTD PMID:25181051 buspirone increases expression ISO RGD:1308519 6480464 Buspirone results in increased expression of POLD4 mRNA CTD PMID:24136188 chlorpromazine increases expression ISO RGD:1318336 6480464 Chlorpromazine analog results in increased expression of POLD4 mRNA CTD PMID:15924885 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of POLD4 mRNA CTD PMID:23811191 cobalt dichloride decreases expression ISO RGD:1318336 6480464 cobaltous chloride results in decreased expression of POLD4 mRNA CTD PMID:19376846 cobalt dichloride decreases expression ISO RGD:1308519 6480464 cobaltous chloride results in decreased expression of POLD4 mRNA CTD PMID:24386269 copper atom decreases expression ISO RGD:1308519 6480464 Copper results in decreased expression of POLD4 mRNA CTD PMID:22465980 copper(0) decreases expression ISO RGD:1308519 6480464 Copper results in decreased expression of POLD4 mRNA CTD PMID:22465980 copper(II) sulfate increases expression ISO RGD:1318336 6480464 Copper Sulfate results in increased expression of POLD4 mRNA CTD PMID:19549813 cyclosporin A decreases expression ISO RGD:1318336 6480464 Cyclosporine results in decreased expression of POLD4 mRNA CTD PMID:20106945 cyclosporin A decreases methylation ISO RGD:1318336 6480464 Cyclosporine results in decreased methylation of POLD4 promoter CTD PMID:27989131 cyclosporin A increases expression ISO RGD:1318336 6480464 Cyclosporine results in increased expression of POLD4 mRNA CTD PMID:25562108 diarsenic trioxide increases expression ISO RGD:1318336 6480464 Arsenic Trioxide results in increased expression of POLD4 mRNA CTD PMID:22521957 diazinon increases methylation ISO RGD:1318336 6480464 Diazinon results in increased methylation of POLD4 gene CTD PMID:22964155 dicrotophos decreases expression ISO RGD:1318336 6480464 dicrotophos results in decreased expression of POLD4 mRNA CTD PMID:28302478 dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of POLD4 mRNA CTD PMID:17441966 doxorubicin increases expression ISO RGD:1318336 6480464 Doxorubicin results in increased expression of POLD4 mRNA CTD PMID:16404146 genistein decreases expression ISO RGD:1318336 6480464 Genistein results in decreased expression of POLD4 mRNA CTD PMID:16474171 gentamycin increases expression ISO RGD:1308519 6480464 Gentamicins results in increased expression of POLD4 mRNA CTD PMID:22061828 guanine multiple interactions ISO RGD:1318336 6480464 Guanine metabolite results in decreased activity of [POLD1 protein binds to POLD2 protein binds to POLD3 protein binds to POLD4 protein], Guanine metabolite results in decreased activity of [POLD1 protein binds to POLD2 protein binds to POLD4 protein] CTD PMID:26010525 hydrogen peroxide affects expression ISO RGD:1318336 6480464 Hydrogen Peroxide affects the expression of POLD4 mRNA CTD PMID:23410634 leflunomide increases expression ISO RGD:1308519 6480464 leflunomide results in increased expression of POLD4 mRNA CTD PMID:24136188 menadione affects expression ISO RGD:1318336 6480464 Vitamin K 3 affects the expression of POLD4 mRNA CTD PMID:23410634 miconazole decreases expression ISO RGD:1308519 6480464 Miconazole results in decreased expression of POLD4 mRNA CTD PMID:22262564 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of POLD4 mRNA CTD PMID:24535843 nefazodone increases expression ISO RGD:1308519 6480464 nefazodone results in increased expression of POLD4 mRNA CTD PMID:24136188 nimesulide increases expression ISO RGD:1308519 6480464 nimesulide results in increased expression of POLD4 mRNA CTD PMID:24136188 ochratoxin A decreases expression ISO RGD:1308519 6480464 ochratoxin A results in decreased expression of POLD4 mRNA CTD PMID:18417182 , PMID:23358140 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of POLD4 mRNA CTD PMID:17562736 phenobarbital affects expression ISO RGD:1318336 6480464 Phenobarbital affects the expression of POLD4 mRNA CTD PMID:19159669 pirinixic acid multiple interactions ISO RGD:1318336 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of POLD4 mRNA CTD PMID:19710929 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of POLD4 mRNA CTD PMID:23811191 quercetin increases expression ISO RGD:1318336 6480464 Quercetin results in increased expression of POLD4 mRNA CTD PMID:21632981 rotenone increases expression ISO RGD:1308519 6480464 Rotenone results in increased expression of POLD4 mRNA CTD PMID:28374803 tamibarotene increases expression ISO RGD:1318336 6480464 tamibarotene results in increased expression of POLD4 mRNA CTD PMID:15498508 tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of POLD4 mRNA CTD PMID:17555576 tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of POLD4 mRNA CTD PMID:15003993 tert-butyl hydroperoxide affects expression ISO RGD:1318336 6480464 tert-Butylhydroperoxide affects the expression of POLD4 mRNA CTD PMID:23410634 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of POLD4 mRNA CTD PMID:19042947 vinclozolin increases expression ISO RGD:1308519 6480464 vinclozolin results in increased expression of POLD4 mRNA CTD PMID:22570695