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Gene: NKX2-3 (NK2 homeobox 3) Homo sapiens
Symbol: NKX2-3
Name: NK2 homeobox 3
CRRD ID: 1318340
Description: Exhibits sequence-specific double-stranded DNA binding activity. Predicted to be involved in several processes, including digestive tract development; hematopoietic or lymphoid organ development; and regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CSX3; homeobox protein NK-2 homolog C; homeobox protein Nkx-2.3; NK2 transcription factor related, locus 3; NK2.3; NKX2.3; NKX2C; NKX4-3
Mus musculus (house mouse) : Nkx2-3 (NK2 homeobox 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nkx2-3 (NK2 homeobox 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nkx2-3 (NK2 homeobox 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NKX2-3 (NK2 homeobox 3)
Canis lupus familiaris (dog) : NKX2-3 (NK2 homeobox 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nkx2-3 (NK2 homeobox 3)
Sus scrofa (pig) : NKX2-3 (NK2 homeobox 3)
Chlorocebus sabaeus (African green monkey) : NKX2-3 (NK2 homeobox 3)
Heterocephalus glaber (naked mole-rat) : Nkx2-3 (NK2 homeobox 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1099,532,942 - 99,536,524 (+)EnsemblGRCh38hg38GRCh38
GRCh381099,532,942 - 99,536,524 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710101,292,690 - 101,296,281 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610101,282,680 - 101,286,271 (+)NCBINCBI36hg18NCBI36
Build 3410101,282,699 - 101,286,268NCBI
Celera1095,029,393 - 95,032,984 (+)NCBI
Cytogenetic Map10q24.2NCBI
HuRef1094,918,911 - 94,922,503 (+)NCBIHuRef
CHM1_110101,575,101 - 101,578,693 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NKX2-3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318340
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.