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Gene: Nkx2-3 (NK2 homeobox 3) Mus musculus
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Symbol: Nkx2-3
Name: NK2 homeobox 3
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ morphogenesis; hematopoietic or lymphoid organ development; and post-embryonic digestive tract morphogenesis. Predicted to localize to nucleus. Is expressed in several structures, including alimentary system; brain; branchial arch; liver; and spleen. Orthologous to human NKX2-3 (NK2 homeobox 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Drosophila NK2 transcription factor related, locus 3; homeobox protein NK-2 homolog 3; homeobox protein NK-2 homolog C; homeobox protein Nkx-2.3; NK2 transcription factor related, locus 3; Nkx-2.3; nkx2-C; Nkx2.3; tinman
Orthologs:
Homo sapiens (human) : NKX2-3 (NK2 homeobox 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nkx2-3 (NK2 homeobox 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nkx2-3 (NK2 homeobox 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NKX2-3 (NK2 homeobox 3)
Canis lupus familiaris (dog) : NKX2-3 (NK2 homeobox 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nkx2-3 (NK2 homeobox 3)
Sus scrofa (pig) : NKX2-3 (NK2 homeobox 3)
Chlorocebus sabaeus (African green monkey) : NKX2-3 (NK2 homeobox 3)
Heterocephalus glaber (naked mole-rat) : Nkx2-3 (NK2 homeobox 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1943,612,325 - 43,615,892 (+)EnsemblGRCm38mm10GRCm38
GRCm381943,612,325 - 43,615,892 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371943,686,815 - 43,690,382 (+)NCBIGRCm37mm9NCBIm37
MGSCv361943,665,636 - 43,669,203 (+)NCBImm8
Celera1944,396,389 - 44,399,962 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1936.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Nkx2-3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318341
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.