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Gene: Lca5 (Leber congenital amaurosis 5 (human)) Mus musculus
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Symbol: Lca5
Name: Leber congenital amaurosis 5 (human)
Description: Involved in intraciliary transport and photoreceptor cell maintenance. Localizes to the axoneme; ciliary basal body; and photoreceptor connecting cilium. Used to study Leber congenital amaurosis 5. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 5. Is expressed in several structures, including nervous system; reproductive system; sensory organ; surface ectoderm; and thymus. Orthologous to human LCA5 (lebercilin LCA5); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930431B11Rik; 5730406O13Rik; AV274874; leber congenital amaurosis 5 protein homolog; Lebercilin; ORF64; riken cdna 4930431b11 gene
Orthologs:
Homo sapiens (human) : LCA5 (lebercilin LCA5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lca5 (lebercilin LCA5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lca5 (lebercilin LCA5)
Pan paniscus (bonobo/pygmy chimpanzee) : LCA5 (lebercilin LCA5)
Canis lupus familiaris (dog) : LCA5 (lebercilin LCA5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lca5 (lebercilin LCA5)
Sus scrofa (pig) : LCA5 (lebercilin LCA5)
Chlorocebus sabaeus (African green monkey) : LCA5 (lebercilin LCA5)
Heterocephalus glaber (naked mole-rat) : Lca5 (lebercilin LCA5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl983,390,293 - 83,441,127 (-)Ensembl
GRCm38983,391,355 - 83,442,994 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37983,284,962 - 83,334,734 (-)NCBIGRCm37mm9NCBIm37
MGSCv36983,188,073 - 83,237,816 (-)NCBImm8
Celera980,483,800 - 80,533,764 (-)NCBICelera
Cytogenetic Map9 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lca5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318397
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.