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Gene: Lca5 (Leber congenital amaurosis 5 (human)) Mus musculus
Symbol: Lca5
Name: Leber congenital amaurosis 5 (human)
Description: Involved in intraciliary transport and photoreceptor cell maintenance. Localizes to the axoneme; ciliary basal body; and photoreceptor connecting cilium. Used to study Leber congenital amaurosis 5. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 5. Is expressed in several structures, including nervous system; reproductive system; sensory organ; surface ectoderm; and thymus. Orthologous to human LCA5 (lebercilin LCA5); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930431B11Rik; 5730406O13Rik; AV274874; leber congenital amaurosis 5 protein homolog; Lebercilin; ORF64; riken cdna 4930431b11 gene
Homo sapiens (human) : LCA5 (lebercilin LCA5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lca5 (lebercilin LCA5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lca5 (lebercilin LCA5)
Pan paniscus (bonobo/pygmy chimpanzee) : LCA5 (lebercilin LCA5)
Canis lupus familiaris (dog) : LCA5 (lebercilin LCA5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lca5 (lebercilin LCA5)
Sus scrofa (pig) : LCA5 (lebercilin LCA5)
Chlorocebus sabaeus (African green monkey) : LCA5 (lebercilin LCA5)
Heterocephalus glaber (naked mole-rat) : Lca5 (lebercilin LCA5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl983,390,293 - 83,441,127 (-)Ensembl
GRCm38983,391,355 - 83,442,994 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37983,284,962 - 83,334,734 (-)NCBIGRCm37mm9NCBIm37
MGSCv36983,188,073 - 83,237,816 (-)NCBImm8
Celera980,483,800 - 80,533,764 (-)NCBICelera
Cytogenetic Map9 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lca5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318397
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.