Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CCR6 (C-C motif chemokine receptor 6) Homo sapiens
Symbol: CCR6
Name: C-C motif chemokine receptor 6
Description: Exhibits C-C chemokine binding activity and C-C chemokine receptor activity. Involved in calcium-mediated signaling; cell chemotaxis; and positive regulation of flagellated sperm motility involved in capacitation. Localizes to cell surface; sperm flagellum; and sperm plasma membrane. Biomarker of several diseases, including IgA glomerulonephritis; cutaneous T cell lymphoma; exanthem; psoriasis; and systemic scleroderma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BN-1; C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; CD196; chemokine (C-C motif) receptor 6; chemokine (C-C) receptor 6; chemokine receptor-like 3; CKR-L3; CKR6; CKRL3; CMKBR6; DCR2; DRY-6; DRY6; G protein-coupled receptor 29; G-protein coupled receptor 29; GPR-CY4; GPR29; GPRCY4; LARC receptor; seven-transmembrane receptor, lymphocyte, 22; STRL22
Mus musculus (house mouse) : Ccr6 (chemokine (C-C motif) receptor 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccr6 (C-C motif chemokine receptor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccr6 (C-C motif chemokine receptor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : CCR6 (C-C motif chemokine receptor 6)
Canis lupus familiaris (dog) : CCR6 (C-C motif chemokine receptor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccr6 (C-C motif chemokine receptor 6)
Sus scrofa (pig) : CCR6 (C-C motif chemokine receptor 6)
Chlorocebus sabaeus (African green monkey) : CCR6 (C-C motif chemokine receptor 6)
Heterocephalus glaber (naked mole-rat) : Ccr6 (C-C motif chemokine receptor 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl6167,111,807 - 167,139,696 (+)EnsemblGRCh38hg38GRCh38
GRCh386167,111,807 - 167,139,141 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376167,525,295 - 167,554,168 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366167,445,285 - 167,472,619 (+)NCBINCBI36hg18NCBI36
Build 346167,506,667 - 167,523,040NCBI
Celera6168,267,636 - 168,294,982 (+)NCBI
Cytogenetic Map6q27NCBI
HuRef6164,997,922 - 165,025,262 (+)NCBIHuRef
CHM1_16167,787,685 - 167,815,011 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CCR6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318406
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.