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Gene: L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2) Homo sapiens
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Symbol: L3MBTL2
Name: L3MBTL histone methyl-lysine binding protein 2
Description: Exhibits methylated histone binding activity. Predicted to be involved in several processes, including ectoderm development; negative regulation of transcription, DNA-templated; and regulation of histone modification. Localizes to nucleus; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; aflatoxin B1; aflatoxin B2.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: H-l(3)mbt-l; H-l(3)mbt-like protein 2; l(3)mbt-like 2; l(3)mbt-like 2 (Drosophila); L(3)mbt-like protein 2; L3MBT; L3MBTL2 polycomb repressive complex 1 subunit; L3MBTL2, polycomb repressive complex 1 subunit; lethal(3)malignant brain tumor-like protein 2; lmbt-like 2 (Drosophila) isoform 1; lmbt-like 2 (Drosophila) isoform 2; lmbt-like 2 isoform 1; lmbt-like 2 isoform 2
Orthologs:
Mus musculus (house mouse) : L3mbtl2 (L3MBTL2 polycomb repressive complex 1 subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : L3mbtl2 (L3MBTL histone methyl-lysine binding protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : L3mbtl2 (L3MBTL histone methyl-lysine binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2)
Canis lupus familiaris (dog) : L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : L3mbtl2 (L3MBTL histone methyl-lysine binding protein 2)
Sus scrofa (pig) : L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2)
Chlorocebus sabaeus (African green monkey) : L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2)
Heterocephalus glaber (naked mole-rat) : L3mbtl2 (L3MBTL histone methyl-lysine binding protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2241,205,282 - 41,231,271 (+)EnsemblGRCh38hg38GRCh38
GRCh382241,205,192 - 41,231,271 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372241,601,312 - 41,627,276 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,931,259 - 39,957,221 (+)NCBINCBI36hg18NCBI36
Build 342239,925,812 - 39,951,774NCBI
Celera2225,407,662 - 25,433,655 (+)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2224,565,907 - 24,591,739 (+)NCBIHuRef
CHM1_12241,560,987 - 41,586,967 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on L3MBTL2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318418
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.