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Gene: Sdhb (succinate dehydrogenase complex, subunit B, iron sulfur (Ip)) Mus musculus
Symbol: Sdhb
Name: succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Description: Predicted to have succinate dehydrogenase (ubiquinone) activity. Predicted to be involved in aerobic respiration; respiratory electron transport chain; and succinate metabolic process. Localizes to the mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone). Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; gastrointestinal stromal tumor; paraganglioma; and pheochromocytoma. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human SDHB (succinate dehydrogenase complex iron sulfur subunit B); PARTICIPATES IN altered citric acid cycle pathway; citric acid cycle pathway; electron transport chain pathway; INTERACTS WITH (+)-dexrazoxane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0710008N11Rik; ip; iron-sulfur subunit of complex II; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex subunit B
Related Pseudogenes: Gm19149  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm384140,961,271 - 140,979,198 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374140,517,186 - 140,535,108 (+)NCBIGRCm37mm9NCBIm37
MGSCv364140,233,347 - 140,251,269 (+)NCBImm8
Celera4142,761,706 - 142,779,666 (+)NCBICelera
Cytogenetic Map4 D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sdhb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318464
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.