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Gene: Spdef (SAM pointed domain containing ets transcription factor) Mus musculus
Symbol: Spdef
Name: SAM pointed domain containing ets transcription factor
CRRD ID: 1318474
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in columnar/cuboidal epithelial cell differentiation; regulation of cell fate commitment; and regulation of transcription by RNA polymerase II. Localizes to nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human SPDEF (SAM pointed domain containing ETS transcription factor); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: P; PDE; PDEF; prostate epithelium-specific Ets transcription factor; prostate specific ets transcription factor; prostate-derived Ets factor; prostate-specific Ets; Pse; SAM pointed domain-containing Ets transcription factor
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391727,933,416 - 27,949,977 (-)NCBI
GRCm381727,714,446 - 27,731,003 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1727,714,352 - 27,728,955 (-)EnsemblGRCm38mm10GRCm38
MGSCv371727,851,392 - 27,865,896 (-)NCBIGRCm37mm9NCBIm37
MGSCv361727,442,039 - 27,456,509 (-)NCBImm8
Celera1728,266,225 - 28,280,705 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Spdef
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318474
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.