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Gene: DKK4 (dickkopf WNT signaling pathway inhibitor 4) Homo sapiens
Symbol: DKK4
Name: dickkopf WNT signaling pathway inhibitor 4
CRRD ID: 1318528
Description: Predicted to have co-receptor binding activity and receptor antagonist activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to localize to extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dickkopf-4; dickkopf-related protein 4; DKK-4; hDkk-4; MGC129562; MGC129563
Mus musculus (house mouse) : Dkk4 (dickkopf WNT signaling pathway inhibitor 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dkk4 (dickkopf WNT signaling pathway inhibitor 4)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Canis lupus familiaris (dog) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dkk4 (dickkopf WNT signaling pathway inhibitor 4)
Sus scrofa (pig) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Chlorocebus sabaeus (African green monkey) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Heterocephalus glaber (naked mole-rat) : Dkk4 (dickkopf WNT signaling pathway inhibitor 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl842,374,063 - 42,377,229 (-)EnsemblGRCh38hg38GRCh38
GRCh38842,373,194 - 42,391,322 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37842,231,586 - 42,234,674 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36842,350,743 - 42,353,831 (-)NCBINCBI36hg18NCBI36
Build 34842,350,743 - 42,353,830NCBI
Celera841,176,301 - 41,179,389 (-)NCBI
Cytogenetic Map8p11.21NCBI
HuRef840,754,805 - 40,757,893 (-)NCBIHuRef
CHM1_1842,278,494 - 42,281,582 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DKK4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318528
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.