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Gene: STK11 (serine/threonine kinase 11) Homo sapiens
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Symbol: STK11
Name: serine/threonine kinase 11
CRRD ID: 1318548
Description: Exhibits several functions, including ATP binding activity; magnesium ion binding activity; and p53 binding activity. Involved in several processes, including cellular protein modification process; positive regulation of cellular metabolic process; and regulation of signal transduction. Localizes to cytosol; mitochondrion; and nucleoplasm. Implicated in Peutz-Jeghers syndrome; cervical mucinous adenocarcinoma; ovarian carcinoma; and pancreatic cancer. Biomarker of breast carcinoma and endometrial cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hLKB1; liver kinase B1; LKB1; PJS; polarization-related protein LKB1; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11 (peutz-jeghers syndrome); serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11
Orthologs:
Mus musculus (house mouse) : Stk11 (serine/threonine kinase 11)  MGI  Alliance
Rattus norvegicus (Norway rat) : Stk11 (serine/threonine kinase 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stk11 (serine/threonine kinase 11)
Pan paniscus (bonobo/pygmy chimpanzee) : STK11 (serine/threonine kinase 11)
Canis lupus familiaris (dog) : STK11 (serine/threonine kinase 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stk11 (serine/threonine kinase 11)
Sus scrofa (pig) : STK11 (serine/threonine kinase 11)
Chlorocebus sabaeus (African green monkey) : STK11 (serine/threonine kinase 11)
Heterocephalus glaber (naked mole-rat) : Stk11 (serine/threonine kinase 11)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl191,177,558 - 1,228,431 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl191,177,558 - 1,228,435 (+)EnsemblGRCh38hg38GRCh38
GRCh38191,205,778 - 1,228,431 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37191,205,798 - 1,228,434 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,156,798 - 1,179,434 (+)NCBINCBI36hg18NCBI36
Build 34191,156,797 - 1,179,434NCBI
Celera191,140,029 - 1,162,667 (+)NCBI
Cytogenetic Map19p13.3NCBI
HuRef19981,572 - 1,004,116 (+)NCBIHuRef
CHM1_1191,205,350 - 1,228,397 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model