Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: GLDC (glycine decarboxylase) Homo sapiens
Analyze
Symbol: GLDC
Name: glycine decarboxylase
Description: Exhibits glycine dehydrogenase (decarboxylating) activity. Involved in glycine catabolic process. Localizes to the mitochondrion; nucleoplasm; and plasma membrane. Implicated in glycine encephalopathy. Biomarker of stomach cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GCE; GCSP; glycine cleavage system P protein; glycine cleavage system protein P; glycine decarboxylase P-protein; glycine dehydrogenase (aminomethyl-transferring); glycine dehydrogenase (decarboxylating); glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase [decarboxylating], mitochondrial; HYGN1; MGC138198; MGC138200; NKH
Orthologs:
Mus musculus (house mouse) : Gldc (glycine decarboxylase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gldc (glycine decarboxylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gldc (glycine decarboxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : GLDC (glycine decarboxylase)
Canis lupus familiaris (dog) : GLDC (glycine decarboxylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gldc (glycine decarboxylase)
Sus scrofa (pig) : GLDC (glycine decarboxylase)
more info ...
Related Pseudogenes: GLDCP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3896,532,464 - 6,645,692 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3796,532,464 - 6,645,692 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3696,522,464 - 6,635,692 (-)NCBINCBI36hg18NCBI36
Build 3496,522,468 - 6,635,650NCBI
Celera96,469,938 - 6,583,174 (-)NCBI
Cytogenetic Map9p24.1NCBI
HuRef96,487,440 - 6,600,082 (-)NCBIHuRef
CHM1_196,533,234 - 6,646,419 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GLDC
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318561
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.