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Gene: Tiam2 (T cell lymphoma invasion and metastasis 2) Mus musculus
Symbol: Tiam2
Name: T cell lymphoma invasion and metastasis 2
Description: Exhibits GTPase activator activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in activation of GTPase activity; positive regulation of axonogenesis; and small GTPase mediated signal transduction. Localizes to cytoplasm and membrane. Is expressed in several structures, including cartilage; central nervous system; genitourinary system; liver; and respiratory system. Orthologous to human TIAM2 (TIAM Rac1 associated GEF 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3000002F19Rik; mKIAA2016; RAS-related C3 botulinum substrate 1, guanine nucleotide exchange factor 1; SIF and TIAM1-like exchange factor; STEF; T-cell lymphoma invasion and metastasis 2; T-lymphoma invasion and metastasis-inducing protein 2; TIAM-2
Homo sapiens (human) : TIAM2 (TIAM Rac1 associated GEF 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tiam2 (TIAM Rac1 associated GEF 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tiam2 (TIAM Rac1 associated GEF 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TIAM2 (TIAM Rac1 associated GEF 2)
Canis lupus familiaris (dog) : TIAM2 (TIAM Rac1 associated GEF 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tiam2 (TIAM Rac1 associated GEF 2)
Sus scrofa (pig) : TIAM2 (TIAM Rac1 associated GEF 2)
Chlorocebus sabaeus (African green monkey) : TIAM2 (TIAM Rac1 associated GEF 2)
Heterocephalus glaber (naked mole-rat) : Tiam2 (TIAM Rac1 associated GEF 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl173,326,573 - 3,531,344 (+)EnsemblGRCm38mm10GRCm38
GRCm38173,326,313 - 3,519,397 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37173,326,573 - 3,519,397 (+)NCBIGRCm37mm9NCBIm37
MGSCv36173,353,689 - 3,475,879 (+)NCBImm8
Celera173,867,789 - 4,054,192 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map171.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Tiam2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318593
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.