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Gene: Rpl11 (ribosomal protein L11) Mus musculus
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Symbol: Rpl11
Name: ribosomal protein L11
Description: Predicted to have several functions, including peroxisome proliferator activated receptor binding activity; ubiquitin ligase inhibitor activity; and ubiquitin protein ligase binding activity. Involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and protein localization to nucleus. Localizes to cytoplasm and nucleolus. Is expressed in cerebral cortex. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 7 and T-cell acute lymphoblastic leukemia. Orthologous to human RPL11 (ribosomal protein L11); PARTICIPATES IN p53 signaling pathway; ribosome biogenesis pathway; translation pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2010203J19Rik; 60S ribosomal protein L11
Orthologs:
Homo sapiens (human) : RPL11 (ribosomal protein L11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rpl11 (ribosomal protein L11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rpl11 (ribosomal protein L11)
Pan paniscus (bonobo/pygmy chimpanzee) : RPL11 (ribosomal protein L11)
Canis lupus familiaris (dog) : RPL11 (ribosomal protein L11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rpl11 (ribosomal protein L11)
Sus scrofa (pig) : RPL11 (ribosomal protein L11)
Chlorocebus sabaeus (African green monkey) : RPL11 (ribosomal protein L11)
Heterocephalus glaber (naked mole-rat) : Rpl11 (ribosomal protein L11)
more info ...
Related Pseudogenes: Gm10036   Gm10288   Gm12901   Gm18114   Gm48909   Gm5093   Gm6745   Gm6905   Gm7384   Gm7589   Gm8900  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl4136,028,265 - 136,053,428 (-)EnsemblGRCm38mm10GRCm38
GRCm384136,049,354 - 136,053,393 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374135,605,863 - 135,609,286 (-)NCBIGRCm37mm9NCBIm37
MGSCv364135,322,024 - 135,325,447 (-)NCBImm8
Celera4134,251,682 - 134,255,104 (-)NCBICelera
Cytogenetic Map4D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rpl11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318595
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.