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Gene: Rpl11 (ribosomal protein L11) Mus musculus
Symbol: Rpl11
Name: ribosomal protein L11
Description: Predicted to have several functions, including peroxisome proliferator activated receptor binding activity; ubiquitin ligase inhibitor activity; and ubiquitin protein ligase binding activity. Involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and protein localization to nucleus. Localizes to cytoplasm and nucleolus. Is expressed in cerebral cortex. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 7 and T-cell acute lymphoblastic leukemia. Orthologous to human RPL11 (ribosomal protein L11); PARTICIPATES IN p53 signaling pathway; ribosome biogenesis pathway; translation pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2010203J19Rik; 60S ribosomal protein L11
Homo sapiens (human) : RPL11 (ribosomal protein L11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rpl11 (ribosomal protein L11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rpl11 (ribosomal protein L11)
Pan paniscus (bonobo/pygmy chimpanzee) : RPL11 (ribosomal protein L11)
Canis lupus familiaris (dog) : RPL11 (ribosomal protein L11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rpl11 (ribosomal protein L11)
Sus scrofa (pig) : RPL11 (ribosomal protein L11)
Chlorocebus sabaeus (African green monkey) : RPL11 (ribosomal protein L11)
Heterocephalus glaber (naked mole-rat) : Rpl11 (ribosomal protein L11)
more info ...
Related Pseudogenes: Gm10036   Gm10288   Gm12901   Gm18114   Gm48909   Gm5093   Gm6745   Gm6905   Gm7384   Gm7589   Gm8900  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl4136,028,265 - 136,053,428 (-)EnsemblGRCm38mm10GRCm38
GRCm384136,049,354 - 136,053,393 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374135,605,863 - 135,609,286 (-)NCBIGRCm37mm9NCBIm37
MGSCv364135,322,024 - 135,325,447 (-)NCBImm8
Celera4134,251,682 - 134,255,104 (-)NCBICelera
Cytogenetic Map4D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rpl11
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318595
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.