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Gene: PIAS4 (protein inhibitor of activated STAT 4) Homo sapiens
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Symbol: PIAS4
Name: protein inhibitor of activated STAT 4
Description: Exhibits SUMO ligase activity and ubiquitin protein ligase binding activity. Involved in negative regulation of transcription, DNA-templated; positive regulation of protein sumoylation; and protein sumoylation. Localizes to cytoplasm and nucleus; PARTICIPATES IN type II interferon signaling pathway; ataxia telangiectasia-mutated (ATM) signaling pathway; hepatitis C pathway; INTERACTS WITH aflatoxin B1; atrazine; cobalt dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 SUMO-protein ligase PIAS4; FLJ12419; MGC35296; PIAS-gamma; Piasg; PIASY; protein inhibitor of activated STAT protein 4; protein inhibitor of activated STAT protein gamma; protein inhibitor of activated STAT protein PIASy; RING-type E3 ubiquitin transferase PIAS4; zinc finger, MIZ-type containing 6; ZMIZ6
Orthologs:
Mus musculus (house mouse) : Pias4 (protein inhibitor of activated STAT 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pias4 (protein inhibitor of activated STAT, 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pias4 (protein inhibitor of activated STAT 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PIAS4 (protein inhibitor of activated STAT 4)
Canis lupus familiaris (dog) : PIAS4 (protein inhibitor of activated STAT 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pias4 (protein inhibitor of activated STAT 4)
Sus scrofa (pig) : PIAS4 (protein inhibitor of activated STAT 4)
Chlorocebus sabaeus (African green monkey) : PIAS4 (protein inhibitor of activated STAT 4)
Heterocephalus glaber (naked mole-rat) : Pias4 (protein inhibitor of activated STAT 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl194,007,736 - 4,039,386 (+)EnsemblGRCh38hg38GRCh38
GRCh38194,007,736 - 4,039,386 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37194,007,749 - 4,038,067 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,958,749 - 3,989,067 (+)NCBINCBI36hg18NCBI36
Build 34193,958,748 - 3,989,066NCBI
Celera193,947,561 - 3,977,562 (+)NCBI
Cytogenetic Map19p13.3NCBI
HuRef193,801,741 - 3,802,439 (+)NCBIHuRef
HuRef193,773,215 - 3,799,042 (+)NCBIHuRef
CHM1_1194,007,220 - 4,038,698 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Nomenclature History
 
More on PIAS4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318687
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.