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Gene: Csk (c-src tyrosine kinase) Mus musculus
Symbol: Csk
Name: c-src tyrosine kinase
Description: Predicted to have several functions, including enzyme binding activity; identical protein binding activity; and proline-rich region binding activity. Involved in negative regulation of cell population proliferation. Localizes to the cell-cell junction. Is expressed in several structures, including branchial arch; future hindbrain; hemolymphoid system; limb; and nervous system. Orthologous to human CSK (C-terminal Src kinase); PARTICIPATES IN platelet-derived growth factor signaling pathway; neurotrophic factor signaling pathway; INTERACTS WITH (R)-adrenaline; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW212630; C-Src kinase; p50CSK; protein-tyrosine kinase MPK-2; tyrosine-protein kinase CSK
Homo sapiens (human) : CSK (C-terminal Src kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Csk (C-terminal Src kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csk (C-terminal Src kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : CSK (C-terminal Src kinase)
Canis lupus familiaris (dog) : CSK (C-terminal Src kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csk (C-terminal Src kinase)
Sus scrofa (pig) : CSK (CSK, non-receptor tyrosine kinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38957,626,646 - 57,653,631 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37957,474,453 - 57,492,987 (-)NCBIGRCm37mm9NCBIm37
MGSCv36957,424,783 - 57,443,317 (-)NCBImm8
Celera954,862,569 - 54,881,336 (-)NCBICelera
Cytogenetic Map9 BNCBI
cM Map931.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Csk
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318781
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.