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Gene: PIEZO1 (piezo type mechanosensitive ion channel component 1) Homo sapiens
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Symbol: PIEZO1
Name: piezo type mechanosensitive ion channel component 1
Description: Predicted to have cation channel activity and mechanosensitive ion channel activity. Involved in positive regulation of cell-cell adhesion mediated by integrin and positive regulation of integrin activation. Localizes to endoplasmic reticulum. Implicated in dehydrated hereditary stomatocytosis 1 and hereditary lymphedema.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DHS; FAM38A; family with sequence similarity 38, member A; KIAA0233; LMPH3; LMPHM6; membrane protein induced by beta-amyloid treatment; Mib; piezo-type mechanosensitive ion channel component 1
Orthologs:
Related Pseudogenes: PIEZO1P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1688,715,338 - 88,785,220 (-)EnsemblGRCh38hg38GRCh38
GRCh381688,715,338 - 88,785,220 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371688,781,746 - 88,851,372 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,309,247 - 87,351,726 (-)NCBINCBI36hg18NCBI36
Build 341687,309,255 - 87,330,160NCBI
Celera1673,852,958 - 73,920,009 (-)NCBI
Cytogenetic Map16q24.3NCBI
HuRef1674,477,633 - 74,549,500 (-)NCBIHuRef
CHM1_11690,193,016 - 90,262,796 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on PIEZO1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318815
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-05-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.