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Gene: ZRANB1 (zinc finger RANBP2-type containing 1) Homo sapiens
Symbol: ZRANB1
Name: zinc finger RANBP2-type containing 1
Description: Exhibits K63-linked polyubiquitin modification-dependent protein binding activity and thiol-dependent ubiquitin-specific protease activity. Involved in several processes, including positive regulation of Wnt signaling pathway; protein deubiquitination; and regulation of cell morphogenesis. Localizes to cytosol and nucleoplasm; INTERACTS WITH 2-hydroxypropanoic acid; all-trans-retinoic acid; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp762P2216; hTrabid; RP11-298J20.4; TRABID; TRAF-binding domain-containing protein; TRAF-binding protein domain; ubiquitin thioesterase ZRANB1; zinc finger Ran-binding domain-containing protein 1; zinc finger, RAN-binding domain containing 1
Mus musculus (house mouse) : Zranb1 (zinc finger, RAN-binding domain containing 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zranb1 (zinc finger RANBP2-type containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zranb1 (zinc finger RANBP2-type containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ZRANB1 (zinc finger RANBP2-type containing 1)
Canis lupus familiaris (dog) : ZRANB1 (zinc finger RANBP2-type containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zranb1 (zinc finger RANBP2-type containing 1)
Sus scrofa (pig) : ZRANB1 (zinc finger RANBP2-type containing 1)
Chlorocebus sabaeus (African green monkey) : ZRANB1 (zinc finger RANBP2-type containing 1)
Heterocephalus glaber (naked mole-rat) : Zranb1 (zinc finger RANBP2-type containing 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl10124,942,123 - 124,988,189 (+)EnsemblGRCh38hg38GRCh38
GRCh3810124,939,489 - 124,988,189 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710126,605,704 - 126,676,005 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610126,620,682 - 126,665,995 (+)NCBINCBI36hg18NCBI36
Build 3410126,620,681 - 126,663,759NCBI
Celera10120,404,500 - 120,449,814 (+)NCBI
Cytogenetic Map10q26.13NCBI
HuRef10120,317,070 - 120,363,002 (+)NCBIHuRef
CHM1_110126,912,463 - 126,957,768 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ZRANB1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318817
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.