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Gene: CREB3 (cAMP responsive element binding protein 3) Homo sapiens
Symbol: CREB3
Name: cAMP responsive element binding protein 3
Description: Exhibits several functions, including CCR1 chemokine receptor binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and cAMP response element binding protein binding activity. Involved in several processes, including positive regulation of chemotaxis; regulation of nucleic acid-templated transcription; and viral latency. Localizes to several cellular components, including the Golgi membrane; integral component of endoplasmic reticulum membrane; and nuclear body.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: basic leucine zipper protein; cAMP-responsive element-binding protein 3; CREB-3; cyclic AMP response element (CRE)-binding protein/activating transcription factor 1; cyclic AMP-responsive element-binding protein 3; leucin zipper proitein; leucine zipper protein; luman; LZIP; MGC15333; MGC19782; sLZIP; transcription factor LZIP-alpha
Mus musculus (house mouse) : Creb3 (cAMP responsive element binding protein 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Creb3 (cAMP responsive element binding protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Creb3 (cAMP responsive element binding protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CREB3 (cAMP responsive element binding protein 3)
Canis lupus familiaris (dog) : CREB3 (cAMP responsive element binding protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Creb3 (cAMP responsive element binding protein 3)
Sus scrofa (pig) : CREB3 (cAMP responsive element binding protein 3)
Chlorocebus sabaeus (African green monkey) : CREB3 (cAMP responsive element binding protein 3)
Heterocephalus glaber (naked mole-rat) : Creb3 (cAMP responsive element binding protein 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl935,732,598 - 35,736,999 (+)Ensembl
GRCh38935,732,666 - 35,736,999 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37935,732,317 - 35,737,005 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,722,317 - 35,727,005 (+)NCBINCBI36hg18NCBI36
Build 34935,722,316 - 35,727,004NCBI
Celera935,665,867 - 35,670,555 (+)NCBI
Cytogenetic Map9p13.3NCBI
HuRef935,687,941 - 35,692,625 (+)NCBIHuRef
CHM1_1935,732,720 - 35,737,408 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CREB3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318829
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.