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Gene: Reck (reversion-inducing-cysteine-rich protein with kazal motifs) Mus musculus
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Symbol: Reck
Name: reversion-inducing-cysteine-rich protein with kazal motifs
Description: Exhibits Wnt-protein binding activity; coreceptor activity involved in canonical Wnt signaling pathway; and endopeptidase inhibitor activity. Involved in several processes, including blood vessel maturation; embryonic forelimb morphogenesis; and negative regulation of metalloendopeptidase activity. Localizes to the Wnt signalosome and plasma membrane. Is expressed in diaphragm; genitourinary system; and skeletal musculature. Orthologous to human RECK (reversion inducing cysteine rich protein with kazal motifs); INTERACTS WITH 1,1-dichloroethene; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: membrane-anchored glycoprotein RECK; MGC169689; mRECK; reversion-inducing cysteine-rich protein with Kazal motifs; Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK); St15; suppression of tumorigenicity 15
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl443,875,530 - 43,944,806 (+)Ensembl
GRCm38443,875,521 - 43,944,806 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37443,888,402 - 43,957,678 (+)NCBIGRCm37mm9NCBIm37
MGSCv36443,896,700 - 43,965,620 (+)NCBImm8
MGSCv36442,710,564 - 42,778,727 (+)NCBImm8
Celera441,986,209 - 41,997,348 (+)NCBICelera
Celera443,902,817 - 43,957,992 (+)NCBICelera
Cytogenetic Map4 B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Reck
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318852
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.