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Gene: Fus (fused in sarcoma) Mus musculus
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Symbol: Fus
Name: fused in sarcoma
Description: Exhibits mRNA 3'-UTR binding activity. Involved in RNA splicing. Localizes to the cytoplasm and nucleus. Used to study amyotrophic lateral sclerosis type 6. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 6; essential tremor; liposarcoma; and neurodegenerative disease. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and lung. Orthologous to human FUS (FUS RNA binding protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D430004D17Rik; D930039C12Rik; Fus1; fusion, derived from t(12,16) malignant liposarcoma; fusion, derived from t(12;16) malignant liposarcoma; hnRNP P2; pigpen; RNA-binding protein FUS; Tls; translocated in liposarcoma
Orthologs:
Homo sapiens (human) : FUS (FUS RNA binding protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fus (FUS RNA binding protein)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : FUS (FUS RNA binding protein)
Canis lupus familiaris (dog) : FUS (FUS RNA binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fus (FUS RNA binding protein)
Sus scrofa (pig) : FUS (FUS RNA binding protein)
Chlorocebus sabaeus (African green monkey) : FUS (FUS RNA binding protein)
Heterocephalus glaber (naked mole-rat) : Fus (FUS RNA binding protein)
more info ...
Related Pseudogenes: Gm10167   Gm7199   Gm8309  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl7127,967,457 - 127,985,701 (+)Ensembl
GRCm387127,966,789 - 127,982,032 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377135,110,993 - 135,125,546 (+)NCBIGRCm37mm9NCBIm37
MGSCv367127,758,702 - 127,773,179 (+)NCBImm8
Celera7127,802,588 - 127,817,000 (+)NCBICelera
Cytogenetic Map7F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Fus
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318883
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.