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Gene: EIF3C (eukaryotic translation initiation factor 3 subunit C) Homo sapiens
Symbol: EIF3C
Name: eukaryotic translation initiation factor 3 subunit C
Description: Exhibits RNA binding activity. Contributes to translation initiation factor activity. Involved in positive regulation of mRNA binding activity; positive regulation of translation; and translational initiation. Localizes to the eukaryotic translation initiation factor 3 complex; PARTICIPATES IN translation initiation pathway; INTERACTS WITH all-trans-retinoic acid; arsenous acid; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cell migration-inducing protein 17; eIF3 p110; eIF3-p110; EIF3CL; EIF3S8; eukaryotic translation initiation factor 3 subunit 8; eukaryotic translation initiation factor 3, subunit 8 (110kD); eukaryotic translation initiation factor 3, subunit 8, 110kDa; eukaryotic translation initiation factor 3, subunit C; FLJ53378; FLJ54400; FLJ54404; FLJ55450; FLJ55750; FLJ78287; MGC189737; MGC189744
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381628,688,558 - 28,735,730 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371628,699,879 - 28,747,051 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,630,283 - 28,654,552 (+)NCBINCBI36hg18NCBI36
Build 341628,630,284 - 28,654,535NCBI
Celera1628,059,155 - 28,083,432 (-)NCBI
Cytogenetic Map16p11.2NCBI
HuRef1626,681,316 - 26,681,588 (+)NCBIHuRef
CHM1_11629,706,766 - 29,758,789 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on EIF3C
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318894
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.