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Gene: ABRAXAS2 (abraxas 2, BRISC complex subunit) Homo sapiens
Symbol: ABRAXAS2
Name: abraxas 2, BRISC complex subunit
Description: Exhibits microtubule binding activity and polyubiquitin modification-dependent protein binding activity. Involved in several processes, including mitotic spindle assembly; protein K63-linked deubiquitination; and response to ischemia. Localizes to BRISC complex and cytoplasm. Colocalizes with microtubule minus-end; midbody; and spindle pole centrosome; INTERACTS WITH 2-hydroxypropanoic acid; cadmium dichloride; deoxynivalenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: abraxas brother 1; abraxas brother protein 1; ABRO1; BRISC complex subunit Abraxas 2; BRISC complex subunit Abro1; FAM175B; family with sequence similarity 175 member B; family with sequence similarity 175, member B; FLJ22338; KIAA0157
Mus musculus (house mouse) : Abraxas2 (BRISC complex subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : Abraxas2 (abraxas 2, BRISC complex subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abraxas2 (abraxas 2, BRISC complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : ABRAXAS2 (abraxas 2, BRISC complex subunit)
Canis lupus familiaris (dog) : ABRAXAS2 (abraxas 2, BRISC complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abraxas2 (abraxas 2, BRISC complex subunit)
Sus scrofa (pig) : ABRAXAS2 (abraxas 2, BRISC complex subunit)
Chlorocebus sabaeus (African green monkey) : ABRAXAS2 (abraxas 2, BRISC complex subunit)
Heterocephalus glaber (naked mole-rat) : Abraxas2 (abraxas 2, BRISC complex subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl10124,801,819 - 124,836,667 (+)EnsemblGRCh38hg38GRCh38
GRCh3810124,801,803 - 124,836,670 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710126,490,354 - 126,525,239 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610126,480,344 - 126,515,229 (+)NCBINCBI36hg18NCBI36
Build 3410126,480,381 - 126,515,226NCBI
Celera10120,264,282 - 120,299,165 (+)NCBI
Cytogenetic Map10q26.13NCBI
HuRef10120,177,285 - 120,211,753 (+)NCBIHuRef
CHM1_110126,772,128 - 126,807,008 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ABRAXAS2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1318962
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.