Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: HM13 (histocompatibility minor 13) Homo sapiens
Analyze
Symbol: HM13
Name: histocompatibility minor 13
CRRD ID: 1319013
Description: Exhibits aspartic endopeptidase activity, intramembrane cleaving; protein homodimerization activity; and ubiquitin protein ligase binding activity. Involved in membrane protein proteolysis involved in retrograde protein transport, ER to cytosol. Localizes to endoplasmic reticulum membrane and rough endoplasmic reticulum.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dJ324O17.1; H13; hIMP1; histocompatibility (minor) 13; histocompatibility 13; IMP-1; IMP1; IMPAS; IMPAS-1; intramembrane protease 1; minor histocompatibility antigen 13; minor histocompatibility antigen H13; MSTP086; presenilin-like protein 3; PSENL3; PSL3; signal peptide peptidase beta; signal peptide peptidase like 1; SPP; SPPL1
Orthologs:
Mus musculus (house mouse) : H13 (histocompatibility 13)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hm13 (histocompatibility minor 13)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hm13 (histocompatibility minor 13)
Pan paniscus (bonobo/pygmy chimpanzee) : HM13 (histocompatibility minor 13)
Canis lupus familiaris (dog) : HM13 (histocompatibility minor 13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hm13 (histocompatibility minor 13)
Sus scrofa (pig) : HM13 (histocompatibility minor 13)
Chlorocebus sabaeus (African green monkey) : HM13 (histocompatibility minor 13)
Heterocephalus glaber (naked mole-rat) : Hm13 (histocompatibility minor 13)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2031,514,410 - 31,577,923 (+)EnsemblGRCh38hg38GRCh38
GRCh382031,514,442 - 31,569,543 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372030,102,213 - 30,158,178 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362029,565,902 - 29,621,031 (+)NCBINCBI36hg18NCBI36
Build 342029,565,901 - 29,591,257NCBI
Celera2026,858,423 - 26,913,551 (+)NCBI
Cytogenetic Map20q11.21NCBI
HuRef2026,890,440 - 26,945,730 (+)NCBIHuRef
CHM1_12030,006,122 - 30,061,281 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on HM13
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319013
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.