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Gene: NLRP9 (NLR family pyrin domain containing 9) Homo sapiens
Symbol: NLRP9
Name: NLR family pyrin domain containing 9
Description: Predicted to have ATP binding activity. Predicted to be involved in defense response to other organism; positive regulation of interleukin-18 production; and pyroptosis. Localizes to inflammasome complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CLR19.1; NACHT, leucine rich repeat and PYD containing 9; NACHT, LRR and PYD containing protein 9; NACHT, LRR and PYD domains-containing protein 9; NALP9; NLR family, pyrin domain containing 9; NOD6; nucleotide-binding oligomerization domain protein 6; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 9; PAN12; PYRIN and NACHT-containing protein 12
Mus musculus (house mouse) : Nlrp9b (NLR family, pyrin domain containing 9B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nlrp9 (NLR family, pyrin domain containing 9)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : NLRP9 (NLR family pyrin domain containing 9)
Canis lupus familiaris (dog) : NLRP9 (NLR family pyrin domain containing 9)
Sus scrofa (pig) : NLRP9 (NLR family pyrin domain containing 9)
Chlorocebus sabaeus (African green monkey) : NLRP9 (NLR family pyrin domain containing 9)
more info ...
Related Pseudogenes: NLRP9P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1955,708,438 - 55,738,402 (-)EnsemblGRCh38hg38GRCh38
GRCh381955,708,438 - 55,738,402 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371956,219,798 - 56,249,768 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,911,610 - 60,941,580 (-)NCBINCBI36hg18NCBI36
Build 341960,911,609 - 60,941,580NCBI
Celera1953,262,092 - 53,294,502 (-)NCBI
Cytogenetic Map19q13.42NCBI
HuRef1952,530,876 - 52,562,520 (-)NCBIHuRef
CHM1_11956,213,523 - 56,243,345 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NLRP9
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319070
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.