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Gene: STAT6 (signal transducer and activator of transcription 6) Homo sapiens
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Symbol: STAT6
Name: signal transducer and activator of transcription 6
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; identical protein binding activity; and protein phosphatase binding activity. Involved in interleukin-4-mediated signaling pathway and positive regulation of transcription by RNA polymerase II. Localizes to cytosol and nucleoplasm. Implicated in lipoid nephrosis; prostate carcinoma; and urinary schistosomiasis. Biomarker of autosomal dominant polycystic kidney disease and prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D12S1644; IL-4-STAT; signal transducer and activator of transcription 6, interleukin-4 induced; STAT, interleukin4-induced; STAT6B; STAT6C; transcription factor IL-4 STAT
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1257,095,408 - 57,132,139 (-)EnsemblGRCh38hg38GRCh38
GRCh381257,095,408 - 57,111,413 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371257,489,187 - 57,505,196 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,775,458 - 55,791,428 (-)NCBINCBI36hg18NCBI36
Build 341255,775,461 - 55,791,428NCBI
Celera1257,143,115 - 57,159,124 (-)NCBI
Cytogenetic Map12q13.3NCBI
HuRef1254,527,593 - 54,543,593 (-)NCBIHuRef
CHM1_11257,456,871 - 57,472,880 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on STAT6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319194
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.