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Gene: Sox8 (SRY (sex determining region Y)-box 8) Mus musculus
Symbol: Sox8
Name: SRY (sex determining region Y)-box 8
CRRD ID: 1319209
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription factor binding activity. Involved in several processes, including animal organ development; nervous system development; and positive regulation of kidney development. Localizes to cytoplasm; nucleus; and transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human SOX8 (SRY-box transcription factor 8); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: SRY-box containing gene 8; transcription factor SOX-8
Homo sapiens (human) : SOX8 (SRY-box transcription factor 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sox8 (SRY-box transcription factor 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox8 (SRY-box transcription factor 8)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX8 (SRY-box transcription factor 8)
Canis lupus familiaris (dog) : SOX8 (SRY-box transcription factor 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox8 (SRY-box transcription factor 8)
Sus scrofa (pig) : SOX8 (SRY-box transcription factor 8)
Chlorocebus sabaeus (African green monkey) : SOX8 (SRY-box transcription factor 8)
Heterocephalus glaber (naked mole-rat) : Sox8 (SRY-box transcription factor 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391725,784,865 - 25,789,666 (-)NCBI
GRCm381725,565,893 - 25,570,686 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,565,892 - 25,570,686 (-)EnsemblGRCm38mm10GRCm38
MGSCv371725,702,838 - 25,707,631 (-)NCBIGRCm37mm9NCBIm37
MGSCv361725,293,493 - 25,298,286 (-)NCBImm8
Celera1726,098,173 - 26,102,970 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Sox8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319209
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.