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Gene: Csf3r (colony stimulating factor 3 receptor (granulocyte)) Mus musculus
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Symbol: Csf3r
Name: colony stimulating factor 3 receptor (granulocyte)
Description: Exhibits granulocyte colony-stimulating factor binding activity. Involved in neutrophil chemotaxis and regulation of myeloid cell differentiation. Predicted to localize to the external side of plasma membrane and receptor complex. Used to study hereditary neutrophilia. Human ortholog(s) of this gene implicated in acute myeloid leukemia; chronic myelomonocytic leukemia; chronic neutrophilic leukemia; myelodysplastic syndrome; and severe congenital neutropenia. Is expressed in several structures, including brain; dorsal aorta; early conceptus; liver; and reproductive system. Orthologous to human CSF3R (colony stimulating factor 3 receptor); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cd114; Csfgr; G-CSF receptor; G-CSF-R; G-CSFR; granulocyte colony-stimulating factor receptor; MGC141472; MGC141473
Orthologs:
Homo sapiens (human) : CSF3R (colony stimulating factor 3 receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Csf3r (colony stimulating factor 3 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf3r (colony stimulating factor 3 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF3R (colony stimulating factor 3 receptor)
Canis lupus familiaris (dog) : CSF3R (colony stimulating factor 3 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf3r (colony stimulating factor 3 receptor)
Sus scrofa (pig) : CSF3R (colony stimulating factor 3 receptor)
more info ...
Related Pseudogenes: Csf1r-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm384126,023,441 - 126,044,975 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374125,701,903 - 125,721,684 (+)NCBIGRCm37mm9NCBIm37
MGSCv364125,527,040 - 125,546,743 (+)NCBImm8
Celera4124,355,298 - 124,375,614 (+)NCBICelera
Cytogenetic Map4 D2.2NCBI
cM Map459.77NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Csf3r
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319272
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.