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Gene: TTLL1 (tubulin tyrosine ligase like 1) Homo sapiens
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Symbol: TTLL1
Name: tubulin tyrosine ligase like 1
Description: Predicted to have tubulin-glutamic acid ligase activity. Predicted to be involved in protein polyglutamylation. Predicted to localize to the cytoplasm; extracellular region; and microtubule; INTERACTS WITH (-)-epigallocatechin 3-gallate; bisphenol A; cisplatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C22orf7; catalytic subunit of neural tubulin polyglutamylase; HS323M22B; PGs3; probable tubulin polyglutamylase TTLL1; tubulin polyglutamylase complex subunit 3; tubulin tyrosine ligase-like family member 1; tubulin tyrosine ligase-like family, member 1; tubulin--tyrosine ligase-like protein 1; tubulin-tyrosine ligase
Orthologs:
Mus musculus (house mouse) : Ttll1 (tubulin tyrosine ligase-like 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ttll1 (tubulin tyrosine ligase like 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttll1 (tubulin tyrosine ligase like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TTLL1 (tubulin tyrosine ligase like 1)
Canis lupus familiaris (dog) : TTLL1 (tubulin tyrosine ligase like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttll1 (tubulin tyrosine ligase like 1)
Sus scrofa (pig) : TTLL1 (tubulin tyrosine ligase like 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382243,039,516 - 43,089,428 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372243,435,522 - 43,485,434 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,765,589 - 41,815,373 (-)NCBINCBI36hg18NCBI36
Build 342241,760,142 - 41,809,927NCBI
Celera2227,346,102 - 27,395,837 (-)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2226,394,153 - 26,443,736 (-)NCBIHuRef
CHM1_12243,395,326 - 43,445,000 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TTLL1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319289
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.