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Gene: Ndufb8 (NADH:ubiquinone oxidoreductase subunit B8) Mus musculus
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Symbol: Ndufb8
Name: NADH:ubiquinone oxidoreductase subunit B8
Description: Predicted to have NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial respiratory chain complex I assembly. Localizes to mitochondrial respiratory chain complex I. Is expressed in several structures, including alimentary system; integumental system; nervous system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH (+)-dexrazoxane; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900010I05Rik; AI987932; CI-ASHI; complex I-ASHI; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; NADH-ubiquinone oxidoreductase ASHI subunit
Orthologs:
Homo sapiens (human) : NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ndufb8 (NADH:ubiquinone oxidoreductase subunit B8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ndufb8 (NADH:ubiquinone oxidoreductase subunit B8)
Pan paniscus (bonobo/pygmy chimpanzee) : NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8)
Canis lupus familiaris (dog) : NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ndufb8 (NADH:ubiquinone oxidoreductase subunit B8)
Sus scrofa (pig) : NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8)
Chlorocebus sabaeus (African green monkey) : NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8)
Heterocephalus glaber (naked mole-rat) : Ndufb8 (NADH:ubiquinone oxidoreductase subunit B8)
more info ...
Related Pseudogenes: 1700028B04Rik   Gm12314   Gm14248  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1944,548,572 - 44,555,440 (-)EnsemblGRCm38mm10GRCm38
GRCm381944,548,571 - 44,555,442 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371944,624,744 - 44,629,905 (-)NCBIGRCm37mm9NCBIm37
MGSCv361944,603,565 - 44,608,726 (-)NCBImm8
Celera1945,317,871 - 45,323,032 (-)NCBICelera
Cytogenetic Map19C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Ndufb8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319299
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.