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Gene: TTF2 (transcription termination factor 2) Homo sapiens
Symbol: TTF2
Name: transcription termination factor 2
Description: Predicted to have DNA-dependent ATPase activity. Predicted to be involved in termination of RNA polymerase II transcription. Localizes to the cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: F2; HuF2; human factor 2; lodestar homolog; lodestar protein; RNA polymerase II termination factor; transcription release factor 2; transcription termination factor, RNA polymerase II; ZGRF6; zinc finger, GRF-type containing 6
Mus musculus (house mouse) : Ttf2 (transcription termination factor, RNA polymerase II)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ttf2 (transcription termination factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttf2 (transcription termination factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TTF2 (transcription termination factor 2)
Canis lupus familiaris (dog) : TTF2 (transcription termination factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttf2 (transcription termination factor 2)
Sus scrofa (pig) : TTF2 (transcription termination factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: TTF2 (Gene ID: 8458) and FOXE1 (Gene ID: 2304) share the TTF2 symbol/alias in common. TTF2 is a widely used alternative name for forkhead box E1 (FOXE1), which can be confused with the official symbol for transcription termination factor 2 (TTF2). [31 May 2018]
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381117,060,303 - 117,107,453 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371117,602,910 - 117,645,492 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361117,404,472 - 117,447,015 (+)NCBINCBI36hg18NCBI36
Build 341117,314,990 - 117,357,531NCBI
Celera1115,831,559 - 115,874,100 (+)NCBI
Cytogenetic Map1p13.1NCBI
HuRef1115,461,465 - 115,503,489 (+)NCBIHuRef
CHM1_11117,717,868 - 117,760,384 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TTF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319323
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.