Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Fkbp5 (FK506 binding protein 5) Mus musculus
Symbol: Fkbp5
Name: FK506 binding protein 5
CRRD ID: 1319339
Description: Predicted to have heat shock protein binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in response to bacterium. Predicted to localize to cytoplasm and nucleoplasm. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; integumental system; and reproductive system. Human ortholog(s) of this gene implicated in major depressive disorder. Orthologous to human FKBP5 (FKBP prolyl isomerase 5); PARTICIPATES IN aldosterone signaling pathway; cortisol signaling pathway; INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 51 kDa FK506-binding protein; 51 kDa FKBP; 51kDa; D17Ertd592; D17Ertd592e; Dit; Dit1; FK506-binding protein 5; FKBP-5; FKBP-51; FKBP51; peptidyl-prolyl cis-trans isomerase FKBP5; PPIase FKBP5; rotamase
Homo sapiens (human) : FKBP5 (FKBP prolyl isomerase 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fkbp5 (FKBP prolyl isomerase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fkbp5 (FKBP prolyl isomerase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : FKBP5 (FKBP prolyl isomerase 5)
Canis lupus familiaris (dog) : FKBP5 (FKBP prolyl isomerase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fkbp5 (FKBP prolyl isomerase 5)
Sus scrofa (pig) : FKBP5 (FKBP prolyl isomerase 5)
Chlorocebus sabaeus (African green monkey) : FKBP5 (FKBP prolyl isomerase 5)
Heterocephalus glaber (naked mole-rat) : Fkbp5 (FKBP prolyl isomerase 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391728,617,727 - 28,705,123 (-)NCBI
GRCm381728,398,753 - 28,486,149 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1728,399,094 - 28,517,527 (-)EnsemblGRCm38mm10GRCm38
MGSCv371728,536,040 - 28,578,001 (-)NCBIGRCm37mm9NCBIm37
MGSCv361728,126,686 - 28,213,677 (-)NCBImm8
Celera1728,952,443 - 28,994,535 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fkbp5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319339
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.