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Gene: Ripk2 (receptor (TNFRSF)-interacting serine-threonine kinase 2) Mus musculus
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Symbol: Ripk2
Name: receptor (TNFRSF)-interacting serine-threonine kinase 2
Description: Predicted to have several functions, including caspase binding activity; protein domain specific binding activity; and protein homodimerization activity. Involved in several processes, including positive regulation of T cell activation; positive regulation of macromolecule metabolic process; and response to bacterium. Predicted to localize to several cellular components, including cytoskeleton; cytosol; and mitochondrion. Orthologous to human RIPK2 (receptor interacting serine/threonine kinase 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2210420D18Rik; CARD3; CARDIAK; CCK; D4Bwg0615e; receptor-interacting serine/threonine-protein kinase 2; RICK; RIP2; tyrosine-protein kinase RIPK2
Orthologs:
Homo sapiens (human) : RIPK2 (receptor interacting serine/threonine kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ripk2 (receptor-interacting serine-threonine kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ripk2 (receptor interacting serine/threonine kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RIPK2 (receptor interacting serine/threonine kinase 2)
Canis lupus familiaris (dog) : RIPK2 (receptor interacting serine/threonine kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ripk2 (receptor interacting serine/threonine kinase 2)
Sus scrofa (pig) : RIPK2 (receptor interacting serine/threonine kinase 2)
Chlorocebus sabaeus (African green monkey) : RIPK2 (receptor interacting serine/threonine kinase 2)
Heterocephalus glaber (naked mole-rat) : Ripk2 (receptor interacting serine/threonine kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl416,122,733 - 16,163,647 (-)EnsemblGRCm38mm10GRCm38
GRCm38416,122,732 - 16,163,678 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37416,050,522 - 16,090,645 (-)NCBIGRCm37mm9NCBIm37
MGSCv36416,050,522 - 16,090,647 (-)NCBImm8
Celera415,919,468 - 15,959,561 (-)NCBICelera
Cytogenetic Map4A2NCBI
cM Map46.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ripk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319358
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.